Simultaneous atomization and ionization of large organic molecules using femtosecond laser ablation
Simultaneous atomization and ionization of large organic molecules using femtosecond laser ablation
复制标题
使用飞秒激光烧蚀同时原子化和电离大有机分子
DOI：
10.1016/s0169-4332(02)00399-9
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发表时间：
2002
影响因子：
6.7
通讯作者：
Y. Hayashizaki
中科院分区：
文献类型：
--
作者：
M. Kurata;F. Tokanai;Y. Matsuo;Tohru Kobayashi;J. Kawai;H. Kumagai;K. Midorikawa;I. Tanihata;Y. Hayashizaki
我们通过实验证明了飞秒激光烧蚀可同时对固体基质上的有机分子进行原子化和电离（fs-SAI）。我们发现有机分子的大多数组成原子通过飞秒激光烧蚀非共振地原子化和电离。这一观察结果与飞秒激光在气相中对环状芳烃进行光电离的观察结果相反，在气相中几乎没有观察到碎片。提出了固体样品的烧蚀等离子体对 fs-SAI 过程的关键贡献。样品分子中稳定同位素的自然丰度比例得到了很好的再现，这证实了fs-SAI可以应用于同位素标记的大有机分子的定量化学分析。
We have experimentally demonstrated femtosecond laser ablation for simultaneous atomization and ionization (fs-SAI) of organic molecules on solid substrates. We find most of the constituent atoms of organic molecules are atomized and ionized non-resonantly by femtosecond laser ablation. This observation is in contrast with that for the photoionization of cyclic aromatic hydrocarbons by femtosecond laser in the gas phase where little fragmentation has been observed. Crucial contribution of ablation plasma of solid sample to fs-SAI process is suggested. The ratio of natural abundance of stable isotopes contained in sample molecules is well reproduced, which confirms fs-SAI can be applied to the quantitative chemical analysis of isotope-labeled large organic molecules.
通过与富集的稳定同位素标记杂交进行多重 DNA 测序和诊断。
影响因子：
7.4
作者：
Arlinghaus,HF;Kwoka,MN;Guo,XQ;Jacobson,KB
通讯作者：
Jacobson,KB