A Novel Wave Reflection Model of the Human Arterial System
A Novel Wave Reflection Model of the Human Arterial System
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DOI：
10.1007/s10558-009-9074-3
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发表时间：
2009-06-01
期刊：
影响因子：
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通讯作者：
Li, John K-J.
中科院分区：
文献类型：
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作者：
Zhang, Hongjun;Li, John K-J.
从反射角度出发，建立了一个频域分布的55节段动脉模型，用于预测大体动脉的压力波形。在任何节点，预测的压力波形是前向传播波形和来自任何可能位置的多个重复反射波形的组合。这种方法确保了任何单一的反射波形都可以追溯到它的起源，从而准确地知道因果关系。根据分支反射系数、末梢血管床特性和壁粘弹性对该模型进行了评估。结果发现，模型预测的压力波形对支路反射系数最为敏感，这导致在支路采用零正向反射假设。模型预测的血压波形与实际血压波形相比，尤其是上肢的血压波形更好。对于下肢，更精细的分割可以进一步改善预测。
A frequency domain distributed 55 segment arterial model was constructed from the reflection perspective to predict pressure waveforms in the large systemic arteries. At any node, the predicted pressure waveform was the combination of a forward propagating waveform and a number of repeatedly reflected waveforms from any possible sites. This approach ensured that any single reflected waveform could be traced back to its origin, and thus the causal-effect relation would be precisely known. This model was evaluated in terms of branch reflection coefficient, terminal vascular bed behavior, and wall viscoelasticity. It was found that the model predicted pressure waveforms were most sensitive to the branch reflection coefficient, and this led to the adoption of the zero-forward reflection assumption at branches. The model-predicted pressure waveforms compared favorably with realistic blood pressure waveforms, especially in the upper limbs. For lower limbs, finer segmentation could further improve the predictions.