QUANTITATIVE SERIAL SECTIONING ANALYSIS - PREVIEW
QUANTITATIVE SERIAL SECTIONING ANALYSIS - PREVIEW
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DOI：
10.1111/j.1365-2818.1983.tb04254.x
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发表时间：
1983-01-01
期刊：
影响因子：
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通讯作者：
DEHOFF, RT
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文献类型：
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作者：
DEHOFF, RT
定量连续切片分析提供了普通体视学分析中可用的所有几何信息。此外，它还克服了用于估计分布函数和拓扑特性的几何模型固有的弱点。它进一步使得微观结构的一些几何方面变得可用，即使在模型假设的情况下，这些几何方面在体视学上也无法获得。在目前的技术水平下，需要付出巨大的努力来从单个样本中制备和分析单个样本。然而，当前一代的图像分析计算机已经具备自动数据收集和分析的能力，并且具有自动化样品制备过程的合理潜力。定量连续切片分析将使体视学中所有优雅的几何概率论证变得过时。这是未来的潮流吗？
Quantitative serial sectioning analysis provides all of the geometric information that is available from ordinary stereological analysis. In addition, it circumvents the weaknesses inherent in geometric models that are used to estimate distribution functions and topological properties. It further makes accessible some geometric aspects of microstructures that are not available stereologically, even with model assumptions. At the present state of the art it requires a prodigious effort to prepare and analyse a single sample from a single specimen. However, the current generation of image analysing computers already has the capability for automating data collection and analysis, and there is reasonable potential for automating the sample preparation procedure. Quantitative serial sectioning analysis would render obsolete all of the elegant geometrical probability arguments of stereology. Is it the wave of the future?