HIV treatment optimism and its predictors among young adults in southern Malawi.
HIV treatment optimism and its predictors among young adults in southern Malawi.
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马拉维南部年轻人对艾滋病毒治疗的乐观态度及其预测因素。
DOI：
10.1080/09540121.2012.748168
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发表时间：
2013
期刊：
影响因子：
1.7
通讯作者：
Namadingo,Hazel
中科院分区：
文献类型：
--
作者：
Yeatman,Sara;Dovel,Kathryn;Conroy,Amy;Namadingo,Hazel
这项研究措施艾滋病毒治疗的乐观和它的预测在马拉维南部的年轻成年人的代表性样本。2010年，1275名年龄在16岁至26岁之间的女性和470名男性被问及他们与接受抗逆转录病毒治疗（ART）的人的接触情况、性风险行为、艾滋病毒状况，我们使用验证性因素分析开发了一个4项量表，该量表认为艾滋病毒对ART的健康威胁不太严重（降低严重性的乐观），并使用一个单一的措施，以捕捉艾滋病毒的感染性降低，由于ART（降低敏感性乐观）的信念。总体而言，答卷人对艾滋病毒治疗的乐观程度较低。女性和使用ART是两种治疗乐观的最大预测因素。我们发现，接触ART患者与严重程度降低的乐观情绪之间存在非线性关系。人谁知道有人对ART，但没有与他们讨论有较低水平的降低严重程度的乐观比人谁不知道任何人对ART和人谁经常讨论治疗与人对ART。在多变量回归模型中，艾滋病毒治疗乐观与男性的性风险行为的所有措施呈正相关，但与女性的非主要合作伙伴的无保护性行为呈负相关。我们的研究结果表明，抗逆转录病毒疗法在马拉维的传播并没有导致广泛的艾滋病毒治疗乐观。这可能反映了抗逆转录病毒疗法的传播相对较晚，艾滋病毒流行病的普遍性，或者由于结构性限制使获得抗逆转录病毒疗法变得复杂，延误了治疗，二线药物供应有限。
This study measures HIV treatment optimism and its predictors in a representative sample of young adults in southern Malawi. In 2010, 1275 women and 470 men between the ages of 16 and 26 were asked about their exposure to people on antiretroviral therapy (ART), sexual risk behavior, HIV status, and beliefs about ART. We used confirmatory factor analysis to develop a 4-item scale of the belief that HIV is a less serious health threat due to ART (reduced-severity optimism) and used a single measure to capture belief in the reduced infectivity of HIV due to ART (reduced-susceptibility optimism). Overall, respondents reported low levels of HIV treatment optimism. Being female and using ART were the largest predictors of both types of treatment optimism. We found a nonlinear relationship between exposure to people on ART and reduced-severity optimism. People who knew someone on ART but did not discuss it with them had lower levels of reduced-severity optimism than people who did not know anyone on ART and people who regularly discussed treatment with someone on ART. In multivariate regression models, HIV treatment optimism was positively associated with all measures of sexual risk behavior among men, but negatively associated with unprotected sex with a nonprimary partner among women. Our findings suggest that the spread of ART in Malawi has not led to widespread HIV treatment optimism. This may reflect the relatively recent spread of ART, the generalized nature of the HIV epidemic, or the fact that access to ART is complicated by structural limitations that delay treatment and limited availability of second-line medicines.