Longitudinal Changes in Performance on Cognitive Screening Tests in Patients with Mild Cognitive Impairment and Alzheimer Disease.
Longitudinal Changes in Performance on Cognitive Screening Tests in Patients with Mild Cognitive Impairment and Alzheimer Disease.
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DOI：
10.1159/000481910
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发表时间：
2017-09
影响因子：
2.3
通讯作者：
Takahashi R
中科院分区：
文献类型：
--
作者：
Li F;Takechi H;Kokuryu A;Takahashi R
应该进一步开发神经心理测试，跟踪阿尔茨海默病(AD)和轻度认知障碍(MCI)诊断后认知功能的变化，包括情景记忆。本研究的受试者包括22例轻度AD患者和11例MCI患者。对他们进行了2年的随访。对参与者进行了简短的认知筛查测试。评估和分析了测试性能的纵向变化。在这项纵向研究中，风景图片记忆测验(SPMT)显示，MCI和AD参与者在两年内都发生了显著变化。简易智力状态检查(MMSE)和词汇流畅性测试-PLATE显示只有AD患者有显著变化。其他测试都显示结果很少或没有下降。SPMT是一种有效观察MCI和AD患者随访期间变化的有用工具。
Neuropsychological tests that can track changes in cognitive functions after diagnosis of Alzheimer disease (AD) and mild cognitive impairment (MCI), including episodic memory, should be further developed. The participants of our study consisted of 22 mild AD patients and 11 MCI patients. They were followed up for 2 years. Brief cognitive screening tests were administered to the participants. Longitudinal changes in test performance were evaluated and analyzed. In this longitudinal study, the Scenery Picture Memory Test (SPMT) showed significant changes over 2 years in both MCI and AD participants. The Mini-Mental State Examination (MMSE) and Word Fluency Test-vegetable showed significant changes only in AD participants. Other tests all showed little or no decline in results. The SPMT can be a useful tool for effectively observing changes during follow-up of MCI and AD patients.