Genetic approaches to ciliate pattern formation: from self-assembly to morphogenesis.
Genetic approaches to ciliate pattern formation: from self-assembly to morphogenesis.
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纤毛虫模式形成的遗传方法：从自组装到形态发生。
DOI：
10.1016/0168-9525(90)90072-e
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发表时间：
1990
期刊：
影响因子：
--
通讯作者：
J. Beisson
中科院分区：
文献类型：
--
作者：
M. Jerka‐Dziadosz;J. Beisson
Schematic representation of the organization and multiplication of basal bodies along ciliary rows (A) and in oral structures (B).(A) Within ciliary rows (as in Fig. 1) the aligned basal bodies (bb) display the same polarit 3, shown by the associated stmcpares for which they act as nucleating centers: a ciliary rootlet (cr) which points towards the right and anterior side of the unit and of the cell; post-ciliary (p) and transverse (0 microtubule ribbons respectively oriented towards the posterior and left side of the unit and of the cell. When basal bodies duplicate~ each old one (crossed circles) generates a new one (open circles) which becomes inserted anteriorly to it with the same polarity and will nucleate new cr, pp and t whose polarity will be that of the mother unit. Conversely, ff by accident, or due to a mutational defect, or after a graft of a piece of cortex, the polarity of some basal bodies is rotated by 180, these basal bodies will generate new ones posteriorly with respect to the cell anteroposterior axis, and their appendages (ciliary rootlets and microtubule ribbons) will develop with a polarity reversed by 180.(B) Multiplication and ordering of basal bodies in oral membranelles. Basal bodies proliferate at random locations in an'anarchic'field close to pre-existing basal bodies. They later become organized in rows and a second wave of in situ basal body duplication occars that follows the same positional rule as in (A). directly determined by that of its mother basal body (Fig. 2A). In contrast, in the oral apparatus, basal bodies first proliferate without apparent order within an'anarchic field', then become organized in rows of defined size, shape and spacing (Fig. 2B). This ordering ends up with a gastrulation-like movement, as the new oral apparatus invaginates into a pouch, at thc bottom of which phagocytosis will take place. Proliferation of somatic basal bodies and morphogenesis of the new oral apparatus are ac companied by reorganization of all the other conical cytoskeletal networks (see Ref. 4 for a review on Paramecium) and by the formation of a new cytoproct (in the anterior division product) and new contractile vacuoles.At the whole cell level, the remodelling of the surface might appear simple, since cell growth proceeds essentially along the anteroposterior axis by an intercalary addition of surface structures (Fig. 2A), so that both the circumferential asymmetry, and the polarity of basal bodies and their associated structures, are clonally transmitted. However, a precise mapping of the cortical structures throughout division of Paramecium; indicates that the cortex is a mosaic of territories whose relative contributions to the surface of the daughter cells are very unequal and are precisely determined by the extent and timing of basal body proliferation (see Fig. 3 and its legend). In summary, although development in ci! iates does not go beyond the clonal perpetuation of a somewhat rigid pattern, it nevertheless requires a complex developmental program in which (1) signals propagate within the cortex to trigger duplication, growth or reorganization of the different structures and (2) the different territories respond to these signals according to their position.
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嗜热四膜虫的双面突变所指定的镜像模式是如何表达的。
DOI：
10.1002/dvg.1020060306
发表时间：
1986
期刊：
Developmental genetics
影响因子：
--
作者：
Frankel,J;Nelsen,EM
通讯作者：
Nelsen,EM
四膜虫口腔结构模式的突变分析。
DOI：
--
发表时间：
1984
期刊：
Journal of embryology and experimental morphology
影响因子：
--
作者：
Frankel,J;Jenkins,LM;Bakowska,J;Nelsen,EM
通讯作者：
Nelsen,EM
DOI：
10.1242/dev.105.3.457
发表时间：
1989
期刊：
Development (Cambridge, England)
影响因子：
--
作者：
Nelsen,EM;Frankel,J
通讯作者：
Frankel,J
嗜热四膜虫错位波状膜突变体的口腔超微结构和口腔发育。
DOI：
10.1111/j.1550-7408.1985.tb03026.x
发表时间：
1985
期刊：
The Journal of protozoology
影响因子：
--
作者：
Lansing,TJ;Frankel,J;Jenkins,LM
通讯作者：
Jenkins,LM
细胞惯用手的非基因遗传。
DOI：
10.1242/dev.105.3.447
发表时间：
1989
期刊：
Development (Cambridge, England)
影响因子：
--
作者：
Nelsen,EM;Frankel,J;Jenkins,LM
通讯作者：
Jenkins,LM