Therapeutic effects of children with refractory epilepsy after vagus nerve stimulation in Taiwan
Therapeutic effects of children with refractory epilepsy after vagus nerve stimulation in Taiwan
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DOI：
10.1016/j.pedneo.2020.07.010
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发表时间：
2020-12-01
影响因子：
2.1
通讯作者：
Wu, Wen-Hsiang
中科院分区：
文献类型：
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作者：
Li, Sung-Tse;Chiu, Nan-Chang;Wu, Wen-Hsiang
背景：迷走神经刺激(VNS)是癫痫的一种附加治疗方法。本研究旨在利用台湾全国登记资料分析VNS治疗难治性癫痫(RE)的疗效，并试图探讨VNS治疗效果的预测因素。方法：本研究收集2007年12月至2014年12月的资料。患者变量包括性别、年龄、VNS植入日期、癫痫持续时间、癫痫发作频率、癫痫类型、病因和抗癫痫药物(AED)史。我们将患者分为三组：第一组为发作频率为每月80次，第二组为每月24-80次，第三组为发作频率
Background: Vagus nerve stimulation (VNS) is used as an add-on treatment for epilepsy. This study aimed to use Taiwanese nationwide registry data to analyze the therapeutic effects of VNS in children with refractory epilepsy (RE) and try to explore predictive factors of VNS treatment effectiveness.Methods: This retrospective study collected data from December 2007 to December 2014. Patient variables included gender, age, VNS implantation date, epilepsy duration, seizure frequency, seizure type, etiology, and antiepileptic drug (AED) history. We divided patients into three groups: Group I as seizure frequency 80 times per month, Group II as seizure frequency 24-80 times per month, and Group III as seizure frequency