Synthesis of novel 1,3-oxazole derivatives with insect growth-inhibiting activities
Synthesis of novel 1,3-oxazole derivatives with insect growth-inhibiting activities
复制标题
DOI：
10.1016/j.cclet.2013.06.033
复制
发表时间：
2013-11
影响因子：
9.1
通讯作者：
Peng Guo;Junhai Huang;Qingchun Huang;X. Qian
中科院分区：
文献类型：
--
作者：
Peng Guo;Junhai Huang;Qingchun Huang;X. Qian
以高氯酸汞（II）为催化剂，硝酸铈（IV）铵为氧化剂，炔丙基酰胺为原料，通过分子内环化反应合成了2-取代-5-恶唑甲醛。这些结构上有趣的结果有利于合成具有粘虫生长调节活性的2，5-二取代-1，3-恶唑。
Straightforward and direct synthesis of 2-substituted-5-oxazolecarbaldehydes was achieved by treating propargylamides with mercury(II) perchlorate as catalyst and ammonium cerium(IV) nitrate as oxidant agent through intramolecular cyclization. These structurally interesting outcomes benefit to synthesize 2,5-disubstituted-1,3-oxazoles with armyworm growth regulating activities.