TRENDS IN FEMALE BREAST-CANCER IN CONNECTICUT AND THE UNITED-STATES
TRENDS IN FEMALE BREAST-CANCER IN CONNECTICUT AND THE UNITED-STATES
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DOI：
10.1016/0895-4356(91)90198-i
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发表时间：
1991-01-01
影响因子：
7.2
通讯作者：
MCKAY, LA
中科院分区：
文献类型：
--
作者：
HOLFORD, TR;ROUSH, GC;MCKAY, LA
研究了1950-1984年美国女性乳腺癌的年龄、时期和队列趋势。S.死亡率和康涅狄格州发病率。所有三组数据的出生队列模式都很明显。 研究结果证实了浸润性乳腺癌的持续增加，提供了一个强大的出生队列模式的证据，在90年的出生队列的时间序列。 这一趋势在很大程度上是真实的，因为队列模式，因为在尸检和盲法活检获得的数据中存在最小的低检出率。 其次，当队列模型应用于乳腺癌死亡率时，有迹象表明近期乳腺癌死亡率略有下降（面对明显的长期增加），这表明乳腺癌死亡率的控制可能在最近几十年有所发展，也许是通过早期检测和改善治疗。 最后，与以前的报告相比，几乎没有证据表明绝经前和绝经后乳腺癌之间的时间趋势存在临床上重要的差异。
Trends for female breast cancer were examined by age, period and cohort for the years 1950-1984 in U. S. mortality and Connecticut incidence. Birth cohort patterns were evident for all three sets of data. The results confirm a continuing increase in invasive breast cancer by providing evidence of a strong birth cohort pattern, over a time series of 90 years of birth cohorts. This trend appears to be real for the most part because of the cohort patterns and because there is minimal underdetection in data obtained by autopsy and blind biopsy. Secondly, when cohort modeling is applied to breast cancer mortality, there is an indication of a modest decline in recent breast cancer mortality (in the face of an apparent long-term increase), which suggests that control of breast cancer mortality may have developed in recent decades, perhaps through earlier detection and improved treatment. Finally, in contrast with a prior report, there is little evidence for a clinically important differences in time trend between pre- and postmenopausal breast cancer.