The histochemistry of the human nail.
The histochemistry of the human nail.
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人类指甲的组织化学。
作者：
A. Jarrett;R. Spearman
刘易斯提出的指甲的组织学划分已通过组织化学方法得到证实。已证明背侧、中间和腹侧甲板之间存在明显差异。上甲板或背甲板似乎具有最坚硬的物理结构，这可能与其高钙含量有关，而不是与其二硫键有关。中间板由不同的基质形成，并且细胞在角化之前比背板经历更少的细胞溶解。该区域形成指甲的主要部分，位于向前生长的背板和向上生长的腹板之间。后者似乎是直接由甲床细胞形成的，当这些细胞向上生长时，它们同时被腹侧和背侧部分携带。指甲疾病可能主要影响一个、两个或所有活跃的生长中心，并且可能因此产生不同的形态学临床表现。
The histological divisions of the nail suggested by Lewis have been confirmed by histochemical methods. Definite differences have been demonstrated between the dorsal, intermediate, and ventral nail plates. The upper or dorsal nail plate appears to have the hardest physical structure, and this is probably related to its high calcium content rather than to its disulfide bonding. The intermediate plate is formed from a different matrix and the cells undergo less cytolysis prior to keratinization than those of the dorsal plate. This region forms the main bulk of the nail and lies between the forward-growing dorsal plate and the upward-growing ventral plate. The latter appears to be formed directly from the cells of the nail bed, and as these grow upward they are simultaneously carried forward by the ventral and dorsal portions. Diseases of the nail may primarily affect one, two, or all of the active growth centers, and it is probably because of this that the diverse morphological clinical appearances are produced.