Once Daily Self-Monitoring of Blood Glucose (SMBG) Improves Glycemic Control in Oral Hypoglycemic Agents (OHA)-Treated Diabetes: SMBG-OHA Follow-Up Study.
Once Daily Self-Monitoring of Blood Glucose (SMBG) Improves Glycemic Control in Oral Hypoglycemic Agents (OHA)-Treated Diabetes: SMBG-OHA Follow-Up Study.
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DOI：
10.1177/1932296815608869
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发表时间：
2015-10-01
影响因子：
5
通讯作者：
Inagaki, Nobuya
中科院分区：
文献类型：
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作者：
Harashima, Shin-Ichi;Nishimura, Akiko;Inagaki, Nobuya
背景技术背景：本研究的目的是比较血糖控制之间的SMBG-OHA study.METHOD：SMBG-OHA研究的96名受试者中，59名被招募为24周，比较后续研究的SMBG-OHA继续和中止科目与2型糖尿病。研究结果的差异，在24周之间的HbA 1c水平的变化，并在SMBG-continued subjects.RESULTS：虽然健康保险不包括SMBG的费用，22.0%的受试者继续SMBG自己的意愿后，SMBG-OHA研究完成。SMBG继续受试者的HbA 1c水平维持在6.81 ± 0.55%至6.64 ± 0.53%。相反，停用SMBG的受试者的HbA 1c水平从7.18 ± 0.63%升高至7.48 ± 0.84%。HbA 1c水平显著差异为0.83 ± 0.25%（95% CI：-1.33至-0.36）。组间HbA 1c变化的差异为-0.46%（95% CI：-0.78至-0.15）。SMBG频率从2.02 ± 1.06次/d降至1.53 ± 0.86次/d。结论：继续SMBG的受试者HbA 1c水平保持不变，但停止SMBG的受试者HbA 1c水平升高。该研究表明，几乎每天一次的SMBG有助于维持非胰岛素治疗的2型糖尿病患者的血糖控制。
BACKGROUND: The aim of this study was to compare glycemic control between SMBG-continued and -discontinued subjects with type 2 diabetes in the SMBG-OHA study.METHOD: Of the 96 subjects from the SMBG-OHA study, 59 were recruited for the 24-week, comparison follow-up study. The study outcomes were the differences in change in HbA1c levels at 24 weeks between the 2 groups, and change in SMBG frequency in SMBG-continued subjects.RESULTS: Although health insurance does not cover the cost of SMBG, 22.0% of subjects continued SMBG of their own will after the SMBG-OHA study was completed. HbA1c levels were maintained from 6.81 ± 0.55% to 6.64 ± 0.53% in SMBG-continued subjects. Conversely, HbA1c levels were increased from 7.18 ± 0.63% to 7.48 ± 0.84% in SMBG-discontinued subjects. HbA1c levels were significantly different by 0.83 ± 0.25% (95% CI: -1.33 to -0.36). The difference in change in HbA1c between the groups was -0.46% (95% CI: -0.78 to -0.15). SMBG frequency was decreased from 2.02 ± 1.06 to 1.53 ± 0.86 times a day.CONCLUSIONS: HbA1c levels were maintained in SMBG-continued subjects but increased in SMBG-discontinued subjects. The study implied that almost once daily SMBG is helpful to maintain glycemic control in non-insulin-treated type 2 diabetes.