The burden of chronic pain: A cross-sectional survey focussing on diseases, immigration, and opioid use
The burden of chronic pain: A cross-sectional survey focussing on diseases, immigration, and opioid use
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DOI：
10.1016/j.pain.2012.07.023
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发表时间：
2012-12-01
期刊：
影响因子：
7.4
通讯作者：
Ekholm, Ola
中科院分区：
文献类型：
--
作者：
Kurita, Geana Paula;Sjogren, Per;Ekholm, Ola
慢性疼痛目前被认为是一个公共卫生问题，给个人和社会带来高昂的代价。为了改善慢性疼痛的预防和治疗，必须进行流行病学研究来评估慢性疼痛。本研究的目的是估计丹麦成年人中慢性疼痛的患病率，并分析疾病、移民和阿片类药物使用等相关因素。这项横断面调查结合了丹麦健康调查（2010 年）中基于个人的信息以及丹麦官方健康和社会经济、基于个人的登记册。简单随机样本由居住在丹麦的 25000 名个体（>= 16 岁）组成。总共有 60.7% 的人完成了邮寄或在线调查问卷。通过多重逻辑回归分析检查关联性。研究人群由 14925 名个体组成，其中慢性疼痛患病率较高（26.8%，95% 置信区间：26.1 至 27.5），阿片类药物消费患病率较高（4.5%）。其他值得注意的方面：（1）心血管疾病和慢性肺部疾病患者的慢性疼痛发生率高于癌症患者； (2) 与具有丹麦背景的个体相比，具有非西方背景的个体报告的疼痛发生率更高、疼痛强度更高、疼痛范围更广；然而，本土丹麦人更频繁地使用阿片类药物。丹麦慢性疼痛和阿片类药物使用的患病率高得惊人，而阿片类药物消费的相关性尚不清楚。 (c) 2012 年国际疼痛研究协会。由 Elsevier B.V 出版。保留所有权利。
Chronic pain is currently considered a public health problem with high costs to the individual and society. To improve prevention and treatment of chronic pain, epidemiologic studies are mandatory for assessing chronic pain. The aims of this study were to estimate the prevalence of chronic pain in the adult Danish population and to analyze associated factors such as diseases, immigration, and opioid use. This cross-sectional survey combines individual-based information from the Danish Health Survey (2010) and official Danish health and socioeconomic, individual-based registers. The simple random sample consisted of 25000 individuals (>= 16 years old) living in Denmark. In all, 60.7% completed a mailed or online questionnaire. Associations were examined with multiple logistic regression analysis. The study population consisted of 14925 individuals in whom a high prevalence of chronic pain (26.8%, 95% confidence interval: 26.1 to 27.5) and a high prevalence of opioid consumption (4.5%) were observed. Other aspects of particular note: (1) a higher prevalence of chronic pain occurred among individuals with cardiovascular and chronic pulmonary diseases than among individuals with cancer; and (2) individuals with a non-Western background reported a higher pain prevalence, higher pain intensities, and more widespread pain than individuals with Danish background; however, opioids were more frequently used by native Danes. The prevalence of chronic pain as well as opioid use in Denmark are alarmingly high, and the relevance of opioid consumption is unknown. (c) 2012 International Association for the Study of Pain. Published by Elsevier B. V. All rights reserved.