Prevalence of dementia in Chinese elderly in Hong Kong
Prevalence of dementia in Chinese elderly in Hong Kong
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DOI：
10.1212/wnl.50.4.1002
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发表时间：
1998-04-01
期刊：
影响因子：
9.9
通讯作者：
Lau, J
中科院分区：
文献类型：
--
作者：
Chiu, HFK;Lam, LCW;Lau, J
本研究采用两阶段设计，调查了香港70岁及以上中国老年人痴呆症的患病率。在第一阶段，研究人员以广东话版的简易精神状态检查访问了1，034名长者。那些得分低于临界点的人和那些得分在正常范围内的子样本在第二阶段接受了采访，以确定那些患有痴呆症的人。在我们的研究对象中，痴呆症的总体加权患病率为6.1 +/-0.7%，处于白人报告的发病率范围的低端。阿尔茨海默病（AD）占64.6%，血管性痴呆占29.3%。我们的研究结果，以及以前在中国人群中的研究，表明中国人的AD率低于白人。在与遗传和环境因素的相互作用有关的不同文化中，痴呆症的流行病学可能存在实质性差异。
This study examines the prevalence of dementia in elderly Chinese aged 70 years and older in Hong Kong using a two-phase design. In phase 1, 1,034 elderly were interviewed with the Cantonese version of the Mini-Mental State Examination. Those who scored below the cutoff points and a subsample of those with scores in the normal range were interviewed in phase 2 to identify those with dementia. The overall weighted prevalence of dementia in our subjects was 6.1 +/- 0.7%, which is at the lower end of the range of rates reported in whites. Alzheimer's disease (AD) accounted for 64.6% and vascular dementia, 29.3%. Our results, together with previous studies in Chinese populations, suggest that the rates of AD in Chinese are low compared with those in whites. Substantial differences are possible in the epidemiology of dementia across cultures related to interactions of genetic and environmental factors.