Clinical characteristics of 161 cases of corona virus disease 2019 (COVID-19) in Changsha
Clinical characteristics of 161 cases of corona virus disease 2019 (COVID-19) in Changsha
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DOI：
10.26355/eurrev_202003_20711
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发表时间：
2020-03-01
影响因子：
3.3
通讯作者：
Zhou, Z-G
中科院分区：
文献类型：
--
作者：
Zheng, F.;Tang, W.;Zhou, Z-G
目的：2019年12月，武汉市暴发新型冠状病毒肺炎疫情，并迅速向全国其他地区蔓延。材料与方法：对长沙市第一医院北医院(长沙市公共卫生治疗中心)2019年1月17日至2月7日收治的确诊病例进行回顾性分析。结果：新冠肺炎患者年龄中位数为45岁(33.5~57岁)。男性患者占49.7%，64.6%的患者有武汉地区的暴露史，31.7%的患者有家庭聚集性。中位发病天数为6天，重症发生率为18.6%。结论：年龄、合并高血压、氧合指数、双肺斑块、淋巴细胞计数升高、C反应蛋白(CRP)、天冬氨酸氨基转移酶(AST)、乳酸脱氢酶(LDH)、肌酸激酶升高可作为病情严重程度的预测指标。
OBJECTIVE: In December 2019, a new type of coronavirus-infected pneumonia broke out in Wuhan and spread rapidly to other parts of the country. The purpose of this study was to investigate the clinical features of coronavirus disease 2019 (COVID-19).MATERIALS AND METHODS: A retrospective analysis was performed on the confirmed cases of COVID-19, who were admitted to the North Hospital of Changsha first Hospital (Changsha Public Health treatment Center) from January 17 to February 7, 2020.RESULTS: The median age of COVID-19 patients was 45 years (range 33.5-57). The male patients accounted for 49.7%, 64.6% of the patients had a history of exposure in Wuhan, and 31.7% had family aggregation. The median days of onset were six, and the incidence of severe illness was 18.6%. Compared with the non-severe group, the severe group showed statistical significance in older age, hypertension, bilateral lung plaque shadow, decrease in lymphocyte count, increase in C-reactive protein (CRP), aspartate aminotransferase (AST), lactate dehydrogenase, and creatine kinase.CONCLUSIONS: Age, combined hypertension, oxygenation index, double lung patch, decreased lymphocyte count, and elevated levels of C-reactive protein, aspartate aminotransferase, lactate dehydrogenase, and creatine kinase can be used as predictors of the disease severity.