2D analysis of polydisperse core-shell nanoparticles using analytical ultracentrifugation.
2D analysis of polydisperse core-shell nanoparticles using analytical ultracentrifugation.
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DOI：
10.1039/c6an02236g
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发表时间：
2016-12-19
期刊：
影响因子：
--
通讯作者：
Peukert W
中科院分区：
文献类型：
--
作者：
Walter J;Gorbet G;Akdas T;Segets D;Demeler B;Peukert W
准确了解纳米粒子的大小、密度和组成对其应用具有重要意义。本文采用分析超速离心法(AUC)研究了多分散核壳纳米粒子的流体力学性质。由于AUC能够以无与伦比的分辨率和细节解析颗粒尺寸分布(PSD)，因此AUC是表征液相纳米颗粒的最精确的技术之一。由于溶剂层和稳定剂壳层对粒子的流体动力学直径和有效密度有很大的影响，所以当分散在液体中时，小的纳米粒子必须被认为是核-壳系统。AUC测量分析物的沉降和扩散传输，这受核壳组成性质的影响。这项工作表明，多分散并因此广泛分布的NPs对当前最先进的数据评估方法构成了重大挑战。现有方法要么没有足够的分辨率，要么不能正确地再现核壳属性。首先，我们通过模拟数据考察了不同数据评估模型的性能。然后，我们提出了一种新的方法来解决NPs的核壳性质。该方法基于参数约束光谱分析，提供了对多分散纳米粒子的尺寸和有效密度的完全访问。我们的研究得到了来自于氧化锌和CuInS2纳米颗粒的实验数据的补充，这两个纳米颗粒没有单分散的PSD。首次通过二维AUC分析方法，以高分辨率解析出这种结构的尺寸和有效密度。介绍了一种利用分析超速离心法对多分散核壳纳米粒子进行二维分析的工具。它可以准确地确定10纳米以下粒子的大小和密度，从而揭示其核壳结构的重要信息。
Accurate knowledge of size, density and composition of nanoparticles (NPs) is of major importance for their applications. In this work the hydrodynamic characterization of polydisperse core-shell NPs by means of analytical ultracentrifugation (AUC) is addressed. AUC is one of the most accurate techniques for the characterization of NPs in the liquid phase because it can resolve particle size distributions (PSDs) with unrivaled resolution and detail. Small NPs have to be considered as core-shell systems when dispersed in a liquid since a solvation layer and stabilizer shell will significantly contribute to the particle’s hydrodynamic diameter and effective density. AUC measures the sedimentation and diffusion transport of the analytes, which are affected by the core-shell compositional properties. This work demonstrates that polydisperse and thus widely distributed NPs pose significant challenges for current state-of-the-art data evaluation methods. Existing methods either have insufficient resolution or do not correctly reproduce the core-shell properties. First, we investigate the performance of different data evaluation models by means of simulated data. Then, we propose a new methodology to address the core-shell properties of NPs. This method is based on the parametrically constrained spectrum analysis and offers complete access to the size and effective density of polydisperse NPs. Our study is complemented using experimental data derived for ZnO and CuInS2 NPs, which do not have a monodisperse PSD. For the first time, the size and effective density of such structures can be resolved with high resolution by means of a two-dimensional AUC analysis approach. A tool for the 2D analysis of polydisperse core-shell nanoparticles using analytical ultracentrifugation is presented. It allows for the accurate determination of sizes and densities of sub-10 nm particles, thereby revealing important information on their core-shell structure.
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影响因子：
16.6
作者：
Karabudak, Engin;Brookes, Emre;Lesnyak, Vladimir;Gaponik, Nikolai;Eychmueller, Alexander;Walter, Johannes;Segets, Doris;Peukert, Wolfgang;Wohlleben, Wendel;Demeler, Borries;Coelfen, Helmut
通讯作者：
Coelfen, Helmut
影响因子：
3.4
作者：
Schuck, P
通讯作者：
Schuck, P
影响因子：
3.9
作者：
Schindler, T.;Schmiele, M.;Unruh, T.
通讯作者：
Unruh, T.
纳米颗粒的大小，各向异性和密度异质性的表征通过沉积速度。
影响因子：
7.4
作者：
Demeler, Borries;Tich-Lam Nguyen;Gorbet, Gary E.;Schirf, Virgil;Brookes, Emre H.;Mulvaney, Paul;El-Ballouli, Ala'a O.;Pan, Jun;Bakr, Osman M.;Demeler, Aysha K.;Uribe, Blanca I. Hernandez;Bhattarai, Nabraj;Whetten, Robert L.
通讯作者：
Whetten, Robert L.
影响因子：
3.3
作者：
Schindler, Torben;Walter, Johannes;Unruh, Tobias
通讯作者：
Unruh, Tobias