RADIATION-THERAPY IN ADENOCARCINOMA OF THE PROSTATE WITH PELVIC LYMPH-NODE INVOLVEMENT ON LYMPHADENECTOMY
RADIATION-THERAPY IN ADENOCARCINOMA OF THE PROSTATE WITH PELVIC LYMPH-NODE INVOLVEMENT ON LYMPHADENECTOMY
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DOI：
10.1016/0360-3016(80)90030-9
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发表时间：
1980-01-01
影响因子：
7
通讯作者：
SONG, KS
中科院分区：
文献类型：
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作者：
BATATA, MA;HILARIS, BS;SONG, KS
从 1970 年到 1978 年，在纪念斯隆-凯特琳癌症中心（美国纽约州纽约市）进行双侧盆腔淋巴结切除术和前列腺 125I 间质植入时，429 例前列腺腺癌患者中有 135 例（31%）出现盆腔淋巴结受累。 28例患者术后仅对整个骨盆或主动脉旁区域进行外部照射。有 (7/13) 和无 (13/24) 外部照射的确定 5 年生存率为 54%；有外照射的无瘤生存率为 15% (2/13)，无外照射的无瘤生存率为 21% (5/24)。 123 名患者 6 个月。到 7 年随访时，原发肿瘤局部控制的 31 例 (25%) 出现远处转移，主要是骨转移，20 例 (16%) 出现局部复发或持续存在，伴或不伴远处扩散。
From 1970 to 1978, 135 of 429 patients with adenocarcinoma of the prostate (31%) had pelvic lymph nodal involvement at the time of bilateral pelvic lymphadenectomy and 125I interstitial implantation of the prostate at Memorial Sloan-Kettering Cancer Center [New York, New York, USA]. Postoperative external irradiation was given in 28 patients to the whole pelvis alone or with the para-aortic region. Determinate 5 yr survival was 54% with (7/13) and without (13/24) external irradiation; tumor-free survival was 15% (2/13) with and 21% (5/24) without external irradiation. Of 123 patients with 6 mo. to 7 yr of follow-up, 31 (25%) with local control of the primary tumor developed distant metastases, mainly osseous, and 20 (16%) had local recurrence or persistence with or without distant spread.