Intermolecular Oxidative C-N Bond Formation under Metal-Free Conditions: Control of Chemoselectivity between Aryl sp2 and Benzylic sp3 C-H Bond Imidation
Intermolecular Oxidative C-N Bond Formation under Metal-Free Conditions: Control of Chemoselectivity between Aryl sp2 and Benzylic sp3 C-H Bond Imidation
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DOI：
10.1021/ja207296y
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发表时间：
2011-10-19
影响因子：
15
通讯作者：
Chang, Sukbok
中科院分区：
文献类型：
--
作者：
Kim, Hyun Jin;Kim, Jiyu;Chang, Sukbok
发展了一种在无过渡金属条件下合成芳烃分子间氧化C-N键的新方法。通过选择分别以邻苯二甲酰亚胺和二苯磺酰亚胺为代表的氮源，实现了芳基SP(2)和苄基SP(3)C-H键亚胺化反应的完全控制。
A new synthetic approach toward intermolecular oxidative C-N bond formation of arenes has been developed under transition-metal-free conditions. Complete control of chemoselectivity between aryl sp(2) and benzylic sp(3) C-H bond imidation was achieved by the choice of nitrogen sources, representatively being phthalimide and dibenzenesulfonimide, respectively.