Some effects of accelerated charged particles on bacterial spores.

Some effects of accelerated charged particles on bacterial spores.
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加速带电粒子对细菌孢子的一些影响。

DOI:
10.1080/09553006814551171
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发表时间:
1968
期刊:
International Journal of Radiation Biology and Related Studies in Physics Chemistry and Medicine
影响因子:
--
通讯作者:
C. Tobias
C. Tobias
中科院分区:
--
文献类型:
--
作者:
E. L. Powers;J. Lyman;C. Tobias

文献摘要

被引文献

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用在重离子直线加速器中加速的剥离原子辐照巨大芽孢杆菌的Dry芽胞。使用了9种不同的离子,每个离子的能量为8·3 MeV/核子,比能量损失(LET)的变化范围从离化的重离子的5keV/µ(总)到Ne~(10+)离子的500keV/µ。在三种实验条件下绘制了每个离子的存活曲线,以区分三类损伤:I类,完全不依赖氧的损伤;II类,只有在辐射过程中存在氧气时才能看到;以及III类,由氧和自由基相互作用产生。I类随着LET的增加而增加,高达190keV/µ,而II和III类在这个范围内保持不变。除此之外,II和III在500keV/µ时约为零,I略有下降。截面值与孢子的实际几何尺寸相对应:较高的LET颗粒在原生质体的任何部分都是致命的;较低的LET颗粒产生横截面大小。
SummaryDry spores of Bacillus megaterium were irradiated with stripped atoms accelerated in the heavy ion linear accelerator. Nine different ions were used, each at 8·3 MeV/nucleon, with specific energy losses (LET) varying from 5 keV/µ (total) for the ionized deuteron up to 500 keV/µ for the Ne10+ ion. Survival curves were constructed for each ion in three experimental conditions allowing distinction among three classes of damage; class I, the completely oxygen-independent damage; class II, that seen only when oxygen is present during irradiation; and class III, that produced by interactions between oxygen and free radicals.Class I increased with increasing LET up to 190 keV/µ while classes II and III are constant in this range. Beyond this, II and III decrease to zero approximately at 500 keV/µ, with I falling slightly. Cross-sectional values correspond with actual geometric dimensions of the spore: a high LET particle is lethal in any part of the protoplast; lower LET particles yield cross-sectional va...