CHEMOPROPHYLAXIS OF SCRAPIE IN MICE
CHEMOPROPHYLAXIS OF SCRAPIE IN MICE
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DOI：
10.1099/0022-1317-72-2-457
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发表时间：
1991-02-01
影响因子：
3.8
通讯作者：
EHLERS, B
中科院分区：
文献类型：
--
作者：
DIRINGER, H;EHLERS, B
三个应用程序的聚阴离子pentosanpolysulfate约2个月前感染的小鼠痒病完全保护动物感染高达100 LD 50，并大大延长了寿命的那些感染100至10000 LD 50。临床诊断通过羊瘙痒症相关原纤维蛋白的免疫印迹分析证实。
Three applications of the polyanion pentosanpolysulphate about 2 months before infection of mice with scrapie completely protected animals infected with up to 100 LD50, and considerably prolonged the lifespan of those infected with 100 to 10000 LD50. The clinical diagnosis was confirmed by immunoblot analysis for the protein of scrapie-associated fibrils.