Predictors of weight status following laparoscopic gastric bypass
Predictors of weight status following laparoscopic gastric bypass
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DOI：
10.1381/096089206778392284
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发表时间：
2006-09-01
期刊：
影响因子：
2.9
通讯作者：
Kelly, John J.
中科院分区：
文献类型：
--
作者：
Ma, Yunsheng;Pagoto, Sherry L.;Kelly, John J.
背景：减肥手术后的体重减轻取决于许多因素，如手术后的时间、基线体重和合并症。方法：我们分析了1999年6月至2004年12月在某学术机构由一名外科医生行腹腔镜Roux-en-Y胃旁路术（RYGBP）的494例患者的体重数据。采用线性回归确定预测1年超额体重减轻% （%EWL）的因素。结果：患者手术时平均年龄为44±9.6 (SD)，以女性居多（83.8%）。合并症的基线患病率包括糖尿病24%，高血压42%，高胆固醇血症15%。基线BMI为51.5±8.5 kg/m(2)。平均住院时间为3.8±4.6天。死亡率为0.6%。RYGBP术后6个月、1年和2年随访体重数据分别为90%、90%和51%。1年平均EWL为65 +/- 15.2%。1年的成功率（>= 50% EWL）为85%。较年轻的年龄和较低的基线体重预示着更大的体重减轻。男性比女性减重更多。糖尿病与较低的EWL有关。抑郁对EWL无显著影响。结论：研究表明，在我们的减肥手术方案中，1年的EWL为65%，成功率为85%。我们发现大多数术前合并症和抑郁症不能预测体重减轻，这可能意味着术前筛查。
Background: Weight loss after bariatric surgery varies and depends on many factors, such as time elapsed since surgery, baseline weight, and co-morbidities.Methods: We analyzed weight data from 494 patients who underwent laparoscopic Roux-en-Y gastric bypass (RYGBP) by one surgeon at an academic institution between June 1999 and December 2004. Linear regression was used to identify factors in predicting % excess weight loss (%EWL) at 1 year.Results: Mean patient age at time of surgery was 44 +/- 9.6 (SD), and the majority were female (83.8%). The baseline prevalence of co-morbidities included 24% for diabetes, 42% for hypertension, and 15% for hypercholesterolemia. Baseline BMI was 51.5 +/- 8.5 kg/m(2). Mean length of hospital stay was 3.8 +/- 4.6 days. Mortality rate was 0.6%. Follow-up weight data were available for 90% of patients at 6 months after RYGBP, 90% at 1 year, and 51% at 2 years. Mean %EWL at 1 year was 65 +/- 15.2%. The success rate (>= 50 %EWL) at 1 year was 85%. Younger age and lower baseline weight predicted greater weight loss. Males lost more weight than females. Diabetes was associated with a lower %EWL. Depression did not significantly predict %EWL.Conclusion: The study demonstrated a 65 %EWL and 85% success rate at 1 year in our bariatric surgery program. Our finding that most pre-surgery co-morbidities and depression did not predict weight loss may have implications for pre-surgery screening.