maxdLoad2 and maxdBrowse: standards-compliant tools for microarray experimental annotation, data management and dissemination.
maxdLoad2 and maxdBrowse: standards-compliant tools for microarray experimental annotation, data management and dissemination.
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MAXDLOAD2和MAXDBROWSE：用于微阵列实验注释，数据管理和传播的符合标准的工具。
DOI：
10.1186/1471-2105-6-264
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发表时间：
2005-11-03
影响因子：
3
通讯作者：
Brass, A
中科院分区：
文献类型：
--
作者：
Hancock, D;Wilson, M;Velarde, G;Morrison, N;Hayes, A;Hulme, H;Wood, AJ;Nashar, K;Kell, DB;Brass, A
MaxDload2是一个关系数据库架构和Java®®微阵列实验注释和存储的应用。格式。服务环境。
MaxDload2向基础关系数据库提供了易于使用的接口，并提供了浏览，搜索和编辑的设施的完整补充。元素，无论其主要新颖特征之间有多少个中间联系。
•可以捕获的元数据的灵活性，
•提供用于从电子表格和其他表格表示的数据的工具，
•为自动创建结构化文档提供的工具，
•通过Web和Web-Services接口浏览和访问数据的能力。
在MaxDload2中，自定义正在捕获或更改元数据的定义的元数据非常简单。专门配置了元数据定义（配置文件），也可以集中式，以响应标准或术语的修订，而无需用户干预而传播给客户。
MaxDBrowse托管在Web服务器上，并向MaxdBrowse的内容提供了多个接口。从数据库中的导出微阵列数据可以通过命令行和肥皂服务器接口进行相同的浏览和搜索功能。通过Web服务体系结构到MAXD数据库。
MaxDload2和MaxDbrowse与所有常见的操作系统和主要数据库服务器兼容。
maxdLoad2 is a relational database schema and Java® application for microarray experimental annotation and storage. It is compliant with all standards for microarray meta-data capture; including the specification of what data should be recorded, extensive use of standard ontologies and support for data exchange formats. The output from maxdLoad2 is of a form acceptable for submission to the ArrayExpress microarray repository at the European Bioinformatics Institute. maxdBrowse is a PHP web-application that makes contents of maxdLoad2 databases accessible via web-browser, the command-line and web-service environments. It thus acts as both a dissemination and data-mining tool. maxdLoad2 presents an easy-to-use interface to an underlying relational database and provides a full complement of facilities for browsing, searching and editing. There is a tree-based visualization of data connectivity and the ability to explore the links between any pair of data elements, irrespective of how many intermediate links lie between them. Its principle novel features are: • the flexibility of the meta-data that can be captured, • the tools provided for importing data from spreadsheets and other tabular representations, • the tools provided for the automatic creation of structured documents, • the ability to browse and access the data via web and web-services interfaces. Within maxdLoad2 it is very straightforward to customise the meta-data that is being captured or change the definitions of the meta-data. These meta-data definitions are stored within the database itself allowing client software to connect properly to a modified database without having to be specially configured. The meta-data definitions (configuration file) can also be centralized allowing changes made in response to revisions of standards or terminologies to be propagated to clients without user intervention. maxdBrowse is hosted on a web-server and presents multiple interfaces to the contents of maxd databases. maxdBrowse emulates many of the browse and search features available in the maxdLoad2 application via a web-browser. This allows users who are not familiar with maxdLoad2 to browse and export microarray data from the database for their own analysis. The same browse and search features are also available via command-line and SOAP server interfaces. This both enables scripting of data export for use embedded in data repositories and analysis environments, and allows access to the maxd databases via web-service architectures. maxdLoad2 and maxdBrowse are portable and compatible with all common operating systems and major database servers. They provide a powerful, flexible package for annotation of microarray experiments and a convenient dissemination environment. They are available for download and open sourced under the Artistic License.
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影响因子：
3
作者：
Killion PJ;Sherlock G;Iyer VR
通讯作者：
Iyer VR
影响因子：
12.3
作者：
Gentleman RC;Carey VJ;Bates DM;Bolstad B;Dettling M;Dudoit S;Ellis B;Gautier L;Ge Y;Gentry J;Hornik K;Hothorn T;Huber W;Iacus S;Irizarry R;Leisch F;Li C;Maechler M;Rossini AJ;Sawitzki G;Smith C;Smyth G;Tierney L;Yang JY;Zhang J
通讯作者：
Zhang J
影响因子：
2
作者：
Rocca-Serra, P;Brazma, A;Sansone, SA
通讯作者：
Sansone, SA
影响因子：
3
作者：
Morrison JL;Breitling R;Higham DJ;Gilbert DR
通讯作者：
Gilbert DR
影响因子：
3
作者：
Maurer M;Molidor R;Sturn A;Hartler J;Hackl H;Stocker G;Prokesch A;Scheideler M;Trajanoski Z
通讯作者：
Trajanoski Z