IRON FORTIFICATION OF INFANT CEREALS - A PROPOSAL FOR THE USE OF FERROUS FUMARATE OR FERROUS SUCCINATE
IRON FORTIFICATION OF INFANT CEREALS - A PROPOSAL FOR THE USE OF FERROUS FUMARATE OR FERROUS SUCCINATE
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DOI：
10.1093/ajcn/49.6.1274
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发表时间：
1989-06-01
影响因子：
7.1
通讯作者：
COOK, JD
中科院分区：
文献类型：
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作者：
HURRELL, RF;FURNISS, DE;COOK, JD
血红蛋白在大鼠，感官的研究，并在人类的铁吸收研究中进行了补充试验，以寻找具有高生物利用度的铁源，可以添加到婴儿谷物作为替代品的铁化合物目前用于强化。从大鼠和感官研究11个替代铁源，富马酸亚铁，琥珀酸亚铁，蔗糖铁被选为最适合的婴儿谷物强化，并通过使用放射性标记，这些化合物的吸收，从强化谷物测定在成年人志愿者。富马酸亚铁和硫酸亚铁之间的吸收没有差异，而琥珀酸亚铁、蔗糖酸亚铁（10% Fe）和焦磷酸铁的值分别为硫酸亚铁值的92%、74%和39%。我们得出结论，富马酸亚铁和琥珀酸亚铁是人体内高度可用的铁源，可用于强化婴儿谷物，而不会导致脂肪氧化或变色。
Hemoglobin-repletion tests in rats, organoleptic studies, and iron-absorption studies in humans were used to search for Fe sources with high bioavailability that could be added to infant cereals as alternatives to the Fe compounds currently used for fortification. From rat and organoleptic studies on 11 alternative Fe sources, ferrous fumarate, ferrous succimate, and ferric saccharate were selected as the most suitable for infant-cereal fortification and, by use of radioactive labels, absorption of those compounds from fortified cereal was measured in adult human volunteers. There was no difference in absorption between ferrous fumarate and ferrous sulfate whereas the values for ferrous succinate, ferrous saccharate (10% Fe), and ferric pyrophosphate were 92%, 74%, and 39% of the ferrous sulfate values, respectively. We conclude that ferrous fumarate and ferrous succinate are highly available Fe sources in man that can be used to fortify infant cereals without causing fat oxidation or discoloration.