Collimonins A-D, Unstable Polyynes with Antifungal or Pigmentation Activities from the Fungus-Feeding Bacterium Collimonas fungivorans Ter331
Collimonins A-D, Unstable Polyynes with Antifungal or Pigmentation Activities from the Fungus-Feeding Bacterium Collimonas fungivorans Ter331
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DOI：
10.1021/acs.orglett.8b01311
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发表时间：
2018-06-15
期刊：
影响因子：
5.2
通讯作者：
Fujita, Makoto
中科院分区：
文献类型：
--
作者：
Kai, Kenji;Sogame, Mai;Fujita, Makoto
本文报道了食真菌Colimonas fungivorans Ter 331中一种新的柯力霉素A D（1-4）的分离和结构鉴定。Collimonins是多氧十六烷酸的新衍生物，包括一个烯-三炔部分。它们的绝对构型完全确定相结合的光谱，化学和结晶海绵的方法。Collimonins对真菌Aspergillus尼日尔ATCC 9029显示出抗真菌或色素沉着活性。
The isolation and structure elucidation of collimonins A D (1-4) from the fungus-feeding bacterium Collimonas fungivorans Ter331 are reported. Collimonins are new derivatives of polyoxygenated hexadecanoic acid, including an ene-triyne moiety. Their absolute configurations were fully determined by combining spectroscopic, chemical, and crystalline sponge methods. Collimonins showed antifungal or pigmentation activities against the fungus Aspergillus niger ATCC 9029.