Evaluating the effect of a haemoglobin spray on size reduction in chronic DFUs: clinical outcomes at 12 weeks.
Evaluating the effect of a haemoglobin spray on size reduction in chronic DFUs: clinical outcomes at 12 weeks.
复制标题
DOI：
10.12968/bjon.2016.25.12.s59
复制
发表时间：
2016-06-23
期刊：
影响因子：
--
通讯作者：
Guttormsen, Karl
中科院分区：
文献类型：
--
作者：
Dawn Hunt, Sharon;Haycocks, Samantha;Guttormsen, Karl
最近的一项多中心观察性评价研究了局部血红蛋白喷雾剂（Granulox，Infirst）作为标准护理的辅助治疗对17例患者（4例女性/13例男性）在4周内20例慢性糖尿病足溃疡（DFU）伤口尺寸缩小的影响。在完成评价的18个伤口中，有14个伤口（1名患者因感染退出）平均减少53.8%（范围：11.9-100%）。患者和临床医生都可以接受该产品，他们都认为该产品易于使用。本文描述了其余13名患者（15处伤口）在4周评价结束后继续使用喷雾剂的结局。(Data 2例患者和1例在4周评价期间愈合的患者不可用。）到12周时，3个伤口（20%）愈合，8个（53%）正在愈合，3个（20%）尺寸增加，1个（7%）愈合缓慢。
A recent multi-centre observational evaluation investigated the effect of a topical haemoglobin spray (Granulox, Infirst), used as an adjunct to standard care, on wound size reduction in 17 patients (4 females/13 males) with 20 chronic diabetic foot ulcers (DFUs) over a 4-week period. In 14 of the 18 wounds that completed the evaluation (one patient dropped out due to an infection) there was a mean reduction of 53.8% (range: 11.9-100%). The product was acceptable to both patients and clinicians, who all found it easy to use. This article describes the outcomes for the remaining 13 patients (with 15 wounds) who continued using the spray after the 4-week evaluation ended. (Data are not available for two patients and the one patient who healed during the 4-week evaluation.) By 12 weeks, three wounds (20%) had healed, eight (53%) were progressing towards healing, three (20%) increased in size and one (7%) was slow healing.