Effect of ethanol on oxgen uptake and on blood glucose concentration in anesthetized rabbits.

Effect of ethanol on oxgen uptake and on blood glucose concentration in anesthetized rabbits.
复制标题

乙醇对麻醉兔吸氧量和血糖浓度的影响。

DOI:
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发表时间:
1962
期刊:
Acta Physiologica Scandinavica
影响因子:
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通讯作者:
E. Perman
E. Perman
中科院分区:
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文献类型:
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作者:
E. Perman

文献摘要

被引文献

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在尿素麻醉的家兔中,输注小剂量乙醇(0.2-0.4 g/kg)可立即增加摄氧量(10 - 15%)。血糖也会升高。摄氧量的增加显然主要不是由于骨骼肌活动的增加或肾上腺髓质的分泌增加,这表明乙醇或其代谢物之一对代谢有直接刺激作用。高血糖明显是由于肾上腺髓质激素分泌增加所致。-需要强调的是,这些乙醇效应是在低剂量范围内获得的。
In urethane-anesthetized rabbits infusions of small doses of ethanol (0.2–0.4 g/kg) produced an immediate increase in oxygen uptake (10–15 per cent). There was also an increase in blood glucose. The increase in oxygen uptake was apparently not primarily due to increased skeletal muscle activity or to increased secretion from the adrenal medulla, and it is suggested that ethanol or one of its metabolites has a direct stimulating effect on the metabolism. The hyperglycemia was apparently due to increased secretion of adrenal medullary hormones. — It is emphasized that these ethanol effects were obtained in a low dose-range.