Quiet echo planar imaging for functional and diffusion MRI
Quiet echo planar imaging for functional and diffusion MRI
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DOI：
10.1002/mrm.26810
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发表时间：
2018-03-01
影响因子：
3.3
通讯作者：
Hajnal, Joseph V.
中科院分区：
文献类型：
--
作者：
Hutter, Jana;Price, Anthony N.;Hajnal, Joseph V.
PurposeTo开发一个专用的安静的回波平面成像能力胎儿功能和扩散扫描，声学的考虑往往妥协的效率和分辨率，以及角度/时间coverage.MethodsThe梯度波形在多频带加速单次激发回波平面成像序列已被重新设计，以尽量减少频谱内容。这包括具有单个基频的正弦读出、恒定相位编码梯度、重叠平滑CAIPIRINHA斑点以及在扩散MRI中合并压碎器的新策略。这些变化，然后调谐结合梯度系统的频率响应function.ResultsMaintained图像质量，SNR，和定量扩散值，同时降低声学噪声高达12 dB（A）的说明在两个成人实验。胎儿实验在10个科目，涵盖了一系列的参数描绘的适应性和提高效率的安静的回波planar imaging. ConclusionPurpose内置的高效多波段胎儿回波平面成像研究，所提出的框架，降低了所有回波平面成像为基础的序列的声学噪声。通过调整梯度频率响应函数进行全面优化，可在安全范围内实现最大时效扫描。这使得雄心勃勃的宫内研究（例如具有高空间/时间分辨率的功能性脑成像和具有高角度/空间分辨率的扩散扫描）能够在可接受的声级下以高效的方式运行。Magn Reson Med 79：1447-1459，2018。(c)2017年作者磁共振医学出版的威利期刊，公司。国际医学磁共振学会（International Society for Magnetic Resonance in Medicine）这是一个开放获取的文章，根据知识共享署名非商业许可证的条款，允许在任何媒体上使用，分发和复制，前提是原始作品被正确引用，并且不用于商业目的。
PurposeTo develop a purpose-built quiet echo planar imaging capability for fetal functional and diffusion scans, for which acoustic considerations often compromise efficiency and resolution as well as angular/temporal coverage.MethodsThe gradient waveforms in multiband-accelerated single-shot echo planar imaging sequences have been redesigned to minimize spectral content. This includes a sinusoidal read-out with a single fundamental frequency, a constant phase encoding gradient, overlapping smoothed CAIPIRINHA blips, and a novel strategy to merge the crushers in diffusion MRI. These changes are then tuned in conjunction with the gradient system frequency response function.ResultsMaintained image quality, SNR, and quantitative diffusion values while reducing acoustic noise up to 12 dB (A) is illustrated in two adult experiments. Fetal experiments in 10 subjects covering a range of parameters depict the adaptability and increased efficiency of quiet echo planar imaging.ConclusionPurpose-built for highly efficient multiband fetal echo planar imaging studies, the presented framework reduces acoustic noise for all echo planar imaging-based sequences. Full optimization by tuning to the gradient frequency response functions allows for a maximally time-efficient scan within safe limits. This allows ambitious in-utero studies such as functional brain imaging with high spatial/temporal resolution and diffusion scans with high angular/spatial resolution to be run in a highly efficient manner at acceptable sound levels. Magn Reson Med 79:1447-1459, 2018. (c) 2017 The Authors Magnetic Resonance in Medicine published by Wiley Periodicals, Inc. on behalf of International Society for Magnetic Resonance in Medicine. This is an open access article under the terms of the Creative Commons Attribution NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.