Some evidence of effects of environmental chemicals on the endocrine system in children.
Some evidence of effects of environmental chemicals on the endocrine system in children.
复制标题
环境化学物质对儿童内分泌系统影响的一些证据。
DOI：
10.1016/j.ijheh.2007.07.005
复制
发表时间：
2007
影响因子：
6
通讯作者：
Ragan,NBeth
中科院分区：
文献类型：
--
作者：
Rogan,WalterJ;Ragan,NBeth
在实验室实验和野生动物中，广泛存在于环境中的污染化学品会影响内分泌功能。虽然人类通常会接触到这些污染化学品，但这种接触通常很低，而且很难证明这种接触对内分泌功能的明显影响。人类的数据，包括暴露于化学剂和内分泌的结果进行审查，包括断奶年龄，青春期年龄，肛门生殖器的距离，出生时的性别比，和证据的强度进行了讨论。虽然污染性化学物质对人体内分泌的干扰在很大程度上尚未得到证实，但基础科学是可靠的，这种影响的可能性是真实的。
Pollutant chemicals that are widespread in the environment can affect endocrine function in laboratory experiments and in wildlife. Although human beings are commonly exposed to such pollutant chemicals, the exposures are generally low and clear effects on endocrine function from such exposures have been difficult to demonstrate. Human data including both exposure to the chemical agent and the endocrine outcome are reviewed here, including age at weaning, age at puberty, anogenital distance, and sex ratio at birth, and the strength of the evidence are discussed. Although endocrine disruption in humans by pollutant chemicals remains largely undemonstrated, the underlying science is sound and the potential for such effects is real.