Capacity for plasticity in the adult owl auditory system expanded by juvenile experience
Capacity for plasticity in the adult owl auditory system expanded by juvenile experience
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DOI：
10.1126/science.279.5356.1531
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发表时间：
1998-03-06
期刊：
影响因子：
56.9
通讯作者：
Knudsen, EI
中科院分区：
文献类型：
--
作者：
Knudsen, EI
在创建多模式空间地图的过程中，视顶盖中的听觉-视觉神经元在听觉空间线索的特定值和视野中的位置之间建立联系。在谷仓猫头鹰中，顶盖神经元在它们对耳间时差(ITD)的调谐和它们的视觉感受野(VRF)的位置之间的匹配中揭示了这些联系。在幼年猫头鹰中，ITD-VRF联系可以通过经验在很大范围内进行调整，但在成年猫头鹰中，调整的范围通常会变得相当有限。在成年猫头鹰中，这种正常的适应范围大大扩大，这些猫头鹰在少年时期就已经学会了异常的ITD-VRF联系。因此，在生命早期学习异常联系的行为在这一途径中留下了持久的痕迹，使不寻常的功能联系能够在成年后根据需要重新建立，即使这些联系所代表的联系已经很长一段时间没有被使用了。
In the process of creating a multimodal map of space, auditory-visual neurons in the optic tectum establish associations between particular values of auditory spatial cues and locations in the visual field. In the barn owl, tectal neurons reveal these associations in the match between their tuning for interaural time differences (ITDs) and the locations of their visual receptive fields (VRFs). In young owls ITD-VRF associations can be adjusted by experience over a wide range, but the range of adjustment normally becomes quite restricted in adults. This normal range of adjustment in adults was greatly expanded in owls that had previously learned abnormal ITD-VRF associations as juveniles. Thus, the act of learning abnormal associations early in life leaves an enduring trace in this pathway that enables unusual functional connections to be reestablished, as needed, in adulthood, even when the associations represented by these connections have not been used for an extended period of time.