Nuclear Lamins in Mammalian Spermatogenesis
Nuclear Lamins in Mammalian Spermatogenesis
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DOI：
10.1007/978-3-642-14773-9_12
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发表时间：
2011-01-01
期刊：
影响因子：
--
通讯作者：
Benavente, Ricardo
中科院分区：
文献类型：
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作者：
Alsheimer, Manfred;Jahn, Daniel;Benavente, Ricardo
核纤层蛋白是核膜的重要结构蛋白成分。生精细胞核纤层的组成和性质与同种体细胞有显著差异。哺乳动物生精细胞选择性表达短核纤层蛋白亚型，表现出几个特点。在本章中，我们总结了什么是已知的生殖细胞特异性核纤层蛋白，并讨论其可能的相关性生殖细胞分化和生育能力。
Nuclear lamins are important structural protein components of the nuclear envelope. The composition and properties of the nuclear lamina of spermatogenic cells differ significantly from those of somatic cells of the same species. Mammalian spermatogenic cells selectively express short lamin isoforms showing several peculiarities. In this chapter, we summarize what is known about germ line-specific lamins and discuss their possible relevance for germ cell differentiation and fertility.