Duplex surface modification of porous poly (lactic acid) scaffold
Duplex surface modification of porous poly (lactic acid) scaffold
复制标题
多孔聚乳酸支架的双相表面改性
DOI：
10.1016/j.matlet.2012.11.092
复制
发表时间：
2013-03-01
影响因子：
3
通讯作者：
Dong, Yinsheng
中科院分区：
文献类型：
--
作者：
Guo, Chao;Cai, Ning;Dong, Yinsheng
采用双重表面改性方法对多孔L-乳酸(PLLA)支架材料进行表面改性和力学性能研究。首先对支架进行表面碱解处理，然后进行短时间的表面涂覆处理。在传统的表面水解法的基础上引入了醋酸处理，结果表明，这种新型的表面碱解处理可以进一步改善PLLA支架的亲水性和表面粗糙度。表面水解还显著提高了支架与涂层的结合强度。明胶-羟基磷灰石杂化涂层的存在大大提高了支架的亲水性、力学性能和磷灰石形成能力。(C)2012爱思唯尔B.V.保留所有权利。
A duplex surface modification method is used to enhance the surface and mechanical properties of porous poly (L-lactic acid) (PLLA) scaffold. The scaffold was first modified by a surface alkali hydrolysis treatment and then it underwent a short-time surface coating process. An acetic acid treatment was introduced to the traditional surface hydrolysis; the result indicates that this novel surface alkali hydrolysis treatment can further improve the hydrophilicity and surface roughness of the PLLA scaffold. Surface hydrolysis also improves the bonding strength of the scaffold with the coating significantly. The existence of the gelatin-hydroxyapatite hybrid coating increases the hydrophilicity, mechanical property and apatite-forming ability of the scaffold considerably. (c) 2012 Elsevier B.V. All rights reserved.