USE OF ALCOHOL, TOBACCO AND COFFEE, AND RISK OF PANCREATIC-CANCER
USE OF ALCOHOL, TOBACCO AND COFFEE, AND RISK OF PANCREATIC-CANCER
复制标题
DOI：
10.1038/bjc.1983.245
复制
发表时间：
1983-01-01
影响因子：
8.8
通讯作者：
BJELKE, E
中科院分区：
文献类型：
--
作者：
HEUCH, I;KVALE, G;BJELKE, E
挪威的一项前瞻性研究对16，713名受试者进行了胰腺癌与饮酒、吸烟和咖啡之间的关系进行了研究，其中发生了63例病例。使用分层逻辑回归技术评估相关性。在考虑的潜在风险因素中，饮酒显示出最强的正相关性，与不饮酒者相比，经常饮酒者的估计相对风险为5.4（P < 0.001）。咀嚼烟草或使用鼻烟也有明显的正相关。对于吸烟，观察到的相关性较弱。不能将抽烟斗和喝咖啡联系起来。一般来说，当分析仅限于组织学证实的病例时，发现了更明确的结果。
Associations between pancreatic cancer and use of alcohol, tobacco and coffee were examined in a Norwegian prospective study of 16,713 individuals in which 63 cases occurred. The associations were assessed using techniques for stratified logistic regression. Of the potential risk factors considered, use of alcohol showed the strongest positive association, with an estimated relative risk of 5.4 for those with a frequent use as compared with non-drinkers (P < 0.001). A clear positive association was also obtained with chewing of tobacco or use of snuff. For cigarette smoking a somewhat weaker association was observed. No association could be established for pipe smoking or coffee drinking. In general, more clear-cut results were found when analysis was restricted to histologically-verified cases.