ELECTRON MICROSCOPIC STUDY IN TWO CASES OF JAKOB‐CREUTZFELDT DISEASE
ELECTRON MICROSCOPIC STUDY IN TWO CASES OF JAKOB‐CREUTZFELDT DISEASE
复制标题
两例雅各布-克罗伊茨费尔特病的电子显微镜研究
DOI：
10.1097/00005072-196510000-00003
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发表时间：
1965
影响因子：
3.2
通讯作者：
M. Weiss
中科院分区：
文献类型：
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作者：
R. Terry;M. Weiss
1.对两例Jakob-CreutzFeldt病患者的活检标本进行了电子显微镜检查。2.这种海绵状态是由于星形细胞和神经元突起扩张所致；星形细胞胞浆的灶性清除可能反映了脑组织电解质的失衡。3.内质网核糖体和内质网池的缺失可能反映了蛋白质代谢的紊乱。4.还发现了一个异常突触，可能还有其他突触的一部分。
1. Two biopsies from patients with Jakob-Creutzfeldt disease were examined with the electron microscope. 2. The status spongiosus in this condition is due to dilatation of astrocytic and neuronal processes; it has been suggested that focal clearing of astrocytic cytoplasm may reflect imbalance of brain electrolytes. 3. Neurons were observed with depleted ribosomes and cisterns of endo-plasmic reticulum, perhaps reflecting derangement of the protein metabolism. 4. One abnormal synapse and probably parts, of others have also been found.