Nucleotide sequence of the genes coding for α, β and γ subunits of the proton-translocating ATPase of Escherichia coli
Nucleotide sequence of the genes coding for α, β and γ subunits of the proton-translocating ATPase of Escherichia coli
复制标题
编码大肠杆菌质子转位ATP酶α、β和γ亚基的基因的核苷酸序列
DOI：
10.1016/0006-291x(81)90494-0
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发表时间：
1981
影响因子：
3.1
通讯作者：
M. Futai
中科院分区：
文献类型：
--
作者：
H. Kanazawa;T. Kayano;K. Mabuchi;M. Futai
测定了大肠杆菌质子易位atp酶基因簇的2328个碱基对的核苷酸序列。该序列覆盖了α亚基基因的大部分、γ亚基基因的整个和β亚基基因的氨基末端部分，以及这些基因的侧翼区域。从DNA序列中推断出这些亚基的氨基酸序列，α亚基和γ亚基分别有513个和287个氨基酸残基。根据推断出的初级结构，估计出每个亚单位可能的二级结构。α和γ基因之间和γ和β基因之间的顺反子间区分别为49和26个碱基对。讨论了密码子在这些基因中使用的意义及其表达。
A nucleotide sequence of 2328 base pairs comprising a portion of the gene cluster for the proton-translocating ATPase of E. coli was determined. The sequence covers most of the gene for α subunit, the entire gene for γ subunit and the amino terminal portion of the gene for β subunit, along with the flanking regions of these genes. The amino acid sequences of these subunits deduced from the DNA sequences indicate that the α and γ subunits have 513 and 287 amino acid residues, respectively. A possible secondary structure for each subunit was estimated from the inferred primary structure. The intercistronic regions between the genes for α and γ and between γ and β are 49 and 26 base pairs, respectively. The significance of codon usage in these genes is discussed in correlation with their expression.
ATP 导致大肠杆菌 F1 ATP 酶分离的 α 亚基构象发生巨大变化。
DOI：
--
发表时间：
1980
期刊：
The Journal of biological chemistry
影响因子：
--
作者：
Dunn,SD
通讯作者：
Dunn,SD