Sniff Nasal Inspiratory Pressure in Healthy Japanese Subjects: Mean Values and Lower Limits of Normal
Sniff Nasal Inspiratory Pressure in Healthy Japanese Subjects: Mean Values and Lower Limits of Normal
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DOI：
10.1159/000167321
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发表时间：
2009-01-01
期刊：
影响因子：
3.7
通讯作者：
Fukuda, Michinari
中科院分区：
文献类型：
--
作者：
Kamide, Naoto;Ogino, Mieko;Fukuda, Michinari
背景：当使用鼻吸气压（SNIP）评估呼吸肌力量时，考虑种族差异很重要。因此，有必要确定日本人群中 SNIP 的平均值和正常下限。目的：确定 SNIP 的平均值和正常下限，用于评估健康日本受试者的吸气肌力量。方法：对 223 名年龄 18-69 岁的健康日本志愿者（112 名男性，111 名女性）进行了研究；没有人有肺部疾病、心脏病、神经肌肉疾病或鼻窦炎病史。为了测量 SNIP，将鼻塞插入一个鼻孔并保持嘴巴闭合。每个受试者都被要求用最大的努力从功能残余量中进行短而尖锐的嗅闻。结果：根据组内相关系数，SNIP 测量在男性和女性中均显示出良好的可重复性。男性平均 SNIP 值为 76.8 +/- 28.9 cm H2O，女性平均 SNIP 值为 60.0 +/- 20.0 cm H2O；男性的这些值显着高于女性（p < 0.01）。逐步多元线性回归分析显示，男性的 SNIP 值与年龄呈负相关，而女性的 SNIP 值与体重指数 (BMI) 呈正相关。 SNIP 的正常下限男性为 32.9 cm H2O，女性为 28.8 cm H2O。结论：在健康的日本受试者中，男性的平均 SNIP 值高于女性。在日本受试者中，SNIP 值似乎与男性年龄和女性 BMI 相关。版权所有 (c) 2008 S. Karger AG，巴塞尔
Background: When assessing respiratory muscle strength using sniff nasal inspiratory pressure ( SNIP), it is important to consider ethnic differences. Therefore, it is necessary to determine the mean values and lower limits of normal for SNIP in the Japanese population. Objective: To determine the mean values and lower limits of normal for SNIP, which is used as an assessment of inspiratory muscle strength, in healthy Japanese subjects. Methods: A total of 223 healthy Japanese volunteers ( 112 men, 111 women), aged 18-69 years, were studied; none had a history of pulmonary disease, heart disease, neuromuscular disease or sinusitis. To measure SNIP, a nasal plug was inserted into one nostril and the mouth was kept closed. Each subject was asked to take short, sharp sniffs with maximal effort from functional residual volume. Results: Based on the intraclass correlation coefficient, SNIP measurements showed good reproducibility in both men and women. The mean SNIP values were 76.8 +/- 28.9 cm H2O in men and 60.0 +/- 20.0 cm H2O in women; the values were significantly higher in men than in women (p < 0.01). On stepwise multiple linear regression analysis, the SNIP values were negatively related to age in men and positively related to body mass index (BMI) in women. The lower limits of normal for SNIP were 32.9 cm H2O in men and 28.8 cm H2O in women. Conclusions: In healthy Japanese subjects, the mean SNIP value was higher in men than in women. In Japanese subjects, SNIP values appear to be related to age in men and BMI in women. Copyright (c) 2008 S. Karger AG, Basel