Efficacy of Surgical Treatments for Squamous Cell Carcinoma of the Temporal Bone: A Literature Review
Efficacy of Surgical Treatments for Squamous Cell Carcinoma of the Temporal Bone: A Literature Review
复制标题
颞骨鳞状细胞癌手术治疗的疗效：文献综述
DOI：
10.1177/019459989411000303
复制
发表时间：
1994
期刊：
影响因子：
--
通讯作者：
I. Janecka
中科院分区：
文献类型：
--
作者：
S. Prasad;I. Janecka
对所有关于颞骨鳞状细胞癌手术治疗的文献进行了综述。未发现随机或非随机对照研究。所有研究均为病例系列，无对照受试者。分析了96篇出版物中的26篇，其中包含144例患者的信息。现有证据提示了几个推论，然而，这些领域应该通过适当设计的随机临床试验进行研究：（1）局限于外耳道的癌症患者的生存率相似，无论是否进行乳突切除术，侧颞骨切除术（TBR）或次全TBR：在侧颞骨切除术中加入放射治疗似乎不能提高生存率;（2）当病变扩展到中耳时，次全乳突根治术的患者生存率明显高于侧位全乳突根治术或乳突根治术：乳突根治术加放疗是否能提高生存率尚不确定;（3）当肿瘤扩展到岩尖时，手术切除的价值尚不清楚;（4）切除受累硬脑膜似乎不能提高生存率;然而，关于切除边缘的数据报道不完整;（5）确定切除受累脑实质或颈内动脉的价值需要进一步研究。
A review of ail publications dealing with surgical treatment for squamous cell carcinoma of the temporal bone was performed. No randomized or nonrandomized control studies were identified. All studies were case series without control subjects. Twenty-six of 96 publications, which contained information on 144 patients, were analyzed. Several inferences are suggested by the available evidence; however, these areas should be investigated by properly designed randomized clinical trials: (1) patients with carcinoma that is confined to the external auditory canal have similar survival, regardless of whether mastoidectomy, lateral temporal bone resection (TBR), or subtotal TBR is performed: the addition of radiation therapy to lateral TBR does not appear to improve survival; (2) when disease extends into the middle ear, survival of patients treated with subtotal TBR appeared to be improved over those treated with lateral TBR or mastoidectomy: it remains uncertain if the addition of radiation therapy to mastoidectomy improves survival; (3) the value of surgical resection when carcinoma extends to involve the petrous apex remains unclear; (4) resection of involved dura mater does not appear to Improve survival; however, Incomplete data regarding margins of resection were reported; and (5) determination of the value of resection of involved brain parenchyma or internal carotid artery will require further study.