Influence of weak hip abductor muscles on joint contact forces during normal walking: probabilistic modeling analysis
Influence of weak hip abductor muscles on joint contact forces during normal walking: probabilistic modeling analysis
复制标题
DOI：
10.1016/j.jbiomech.2013.06.030
复制
发表时间：
2013-09-03
影响因子：
2.4
通讯作者：
Jonkers, Ilse
中科院分区：
文献类型：
--
作者：
Valente, Giordano;Taddei, Fulvia;Jonkers, Ilse
髋关节外展肌无力与下肢关节骨关节炎有关，关节超负荷可能会增加疾病进展的风险。肌肉力量、结构性关节退化和关节负荷之间的关系使得后者成为疾病发作和随访研究的重要参数。由于髋关节外展肌无力与关节负荷之间的关系仍然是一个悬而未决的问题，本研究的目的是采用概率建模方法来深入了解髋关节外展肌无力在正常步态不改变的情况下如何影响同侧关节接触力。将通用肌肉骨骼模型缩放到研究中包括的每个健康受试者，并且扰动模型中每个髋关节外展肌的最大力产生能力，以评估髋关节外展肌无力的所有生理上可能的配置如何影响步行期间的关节接触力。一般来说，肌肉系统能够补偿外展肌的无力。外展肌产力能力的降低对关节接触力产生了轻微影响，第 50 个百分位数的平均差异高达 0.5 BW（最大 1.7 BW）。膝关节峰值负荷的增加比髋部或踝关节负荷的增加更大。臀中肌，特别是前室，是对髋部和膝部负荷影响最大的外展肌。进一步的研究应该评估关节负荷的增加是否会影响骨关节炎的发生和进展。 (C) 2013 Elsevier Ltd. 保留所有权利。
The weakness of hip abductor muscles is related to lower-limb joint osteoarthritis, and joint overloading may increase the risk for disease progression. The relationship between muscle strength, structural joint deterioration and joint loading makes the latter an important parameter in the study of onset and follow-up of the disease. Since the relationship between hip abductor weakness and joint loading still remains an open question, the purpose of this study was to adopt a probabilistic modeling approach to give insights into how the weakness of hip abductor muscles, in the extent to which normal gait could be unaltered, affects ipsilateral joint contact forces. A generic musculoskeletal model was scaled to each healthy subject included in the study, and the maximum force-generating capacity of each hip abductor muscle in the model was perturbed to evaluate how all physiologically possible configurations of hip abductor weakness affected the joint contact forces during walking. In general, the muscular system was able to compensate for abductor weakness. The reduced force-generating capacity of the abductor muscles affected joint contact forces to a mild extent, with 50th percentile mean differences up to 0.5 BW (maximum 1.7 BW). There were greater increases in the peak knee joint loads than in loads at the hip or ankle. Gluteus medius, particularly the anterior compartment, was the abductor muscle with the most influence on hip and knee loads. Further studies should assess if these increases in joint loading may affect initiation and progression of osteoarthritis. (C) 2013 Elsevier Ltd. All rights reserved.