Acute kidney injury in a single neonatal intensive care unit in Turkey
Acute kidney injury in a single neonatal intensive care unit in Turkey
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DOI：
10.1007/s12519-012-0371-3
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发表时间：
2013-11-01
影响因子：
8.7
通讯作者：
Nuhoglu, Asiye
中科院分区：
文献类型：
--
作者：
Bolat, Fatih;Comert, Serdar;Nuhoglu, Asiye
背景：虽然围产期医学的进步提高了危重新生儿的存活率，但急性肾损伤(AKI)仍然是新生儿重症监护病房死亡和发病的主要原因之一。方法：对2009年1月至2011年1月住院的1992例新生儿急性心肌梗死患者168例进行回顾性分析。AKI的诊断依据是血肌酐水平1.5 mg/dL，在出生后48小时内持续24小时以上或每天升高0.3 mg/dL以上，且母亲肾功能正常。结果：AKI患病率为8.4%。AKI的常见原因是呼吸窘迫综合征，其次是败血症、窒息、脱水、先天性尿路异常、先天性心脏病和药物治疗。出生体重<1500g者AKI患病率约为出生体重>1500g者的3倍(P
Background: Although advances in perinatal medicine have increased the survival rates of critically ill neonates, acute kidney injury (AKI) is still one of the major causes of mortality and morbidity in neonatal intensive care units. This study aimed to determine the prevalence of AKI and analyze demographic data and risk factors associated with the mortality or morbidity.Methods: Of 1992 neonates hospitalized between January 2009 and January 2011, 168 with AKI were reviewed in the study. The diagnosis of AKI was based on plasma creatinine level >1.5 mg/dL, which persists for more than 24 hours or increases more than 0.3 mg/dL per day after the first 48 hours of birth while showing normal maternal renal function.Results: The prevalence of AKI was 8.4%. The common cause of AKI was respiratory distress syndrome, followed by sepsis, asphyxia, dehydration, congenital anomalies of the urinary tract, congenital heart disease, and medication. The prevalence of AKI in neonates with birth weight lower than 1500 g was about three-fold higher than in those with birth weight higher than 1500 g (P