A comparative study of drug resistance mechanism associated with active site and non-active site mutations: I388N and D425G mutants of acetyl-coenzyme-A carboxylase.
A comparative study of drug resistance mechanism associated with active site and non-active site mutations: I388N and D425G mutants of acetyl-coenzyme-A carboxylase.
复制标题
活性位点和非活性位点突变相关耐药机制的比较研究：乙酰辅酶A羧化酶I388N和D425G突变体。
DOI：
10.2174/157340912799218480
复制
发表时间：
2012-02
影响因子：
1.7
通讯作者：
Yang, Guang-Fu
中科院分区：
文献类型：
--
作者：
Zhu, Xiao-Lei;Yang, Guang-Fu
乙酰辅酶A羧基酶抑制(ACCase；EC 6.4.1.2)除草剂开发中的一个主要问题是由于在CT区域内选择不同的突变而出现抗药性。与抗药性相关的突变一直是
A major concern in the development of acetyl-CoA carboxylase-inhibiting (ACCase; EC 6.4.1.2) herbicides is the emergence of resistance as a result of the selection of distinct mutations within the CT domain. Mutations associated with resistance have been