Asymmetric C-C Bond Forming Reactions by Chiral Crown Catalysts; Darzens Condensation and Nitroalkane Addition to the Double Bond
Asymmetric C-C Bond Forming Reactions by Chiral Crown Catalysts; Darzens Condensation and Nitroalkane Addition to the Double Bond
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手性冠催化剂的不对称 C-C 键形成反应；
作者：
Péter Bakó;Å. Szöllösy;P. Bombicz;L. Tőke,
合成了一种新型的、高效的糖衍生物修饰的冠醚1，它在2-硝基丙烷与查尔酮的Michael加成反应（60%ee）和苯甲酰甲基氯与苯甲醛的Darfonyl缩合反应（64%ee）中表现出明显的相转移催化作用，同时使PT过程由固-液相转变为液-液相。
A new, efficient crown ether 1 anellated to a sugar derivative has been prepared which shows significant asymmetric induction as phase transfer catalyst in the Michael addition of 2-nitropropane to chalcone (60% ee for the S antipode) and in the Darzens condensation of phenacyl chloride and benzaldehyde (64% ee), simultaneously changing the PT process from solid-liquid to liquid-liquid phase.