Malignant pleural effusion:: Prognostic factors for survival and response to chemical pleurodesis in a series of 120 cases
Malignant pleural effusion:: Prognostic factors for survival and response to chemical pleurodesis in a series of 120 cases
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DOI：
10.1159/000029240
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发表时间：
1998-03-01
期刊：
影响因子：
3.7
通讯作者：
Sanchis, F
中科院分区：
文献类型：
--
作者：
Martínez-Moragón, E;Aparicio, J;Sanchis, F
化学胸膜固定术是恶性胸腔积液的有效治疗方法，但适应症必须个体化，以优化其结果。本研究的目的是调查各种预后特征与胸膜固定术的反应率和患者生存概率的关系。进行了一项非同期队列研究，其中120例可评价的恶性胸腔积液患者接受了胸膜固定术。肺癌（40%）、乳腺癌（26.6%）和原发部位不明癌（12.5%）是最常见的肿瘤。分析临床资料和胸水参数。中位总生存期为9个月。胸水葡萄糖（
Chemical pleurodesis is an effective treatment of malignant pleural effusions, but indications must be individualised to optimise its results. The aim of the present study was to investigate the relationship of various prognostic features with both the response rate to pleurodesis and the probability of patient survival. A non-concurrent cohort study was carried out in which 120 evaluable patients with malignant pleural effusion underwent pleurodesis. Lung (40%), breast (26.6%), and unknown primary site (12.5%) carcinomas were the most frequent neoplasms. Clinical data and pleural fluid parameters were analysed. Median overall survival was 9 months. Pleural fluid glucose (