Using Physical Organic Parameters To Correlate Asymmetric Catalyst Performance
Using Physical Organic Parameters To Correlate Asymmetric Catalyst Performance
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DOI：
10.1021/jo4002239
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发表时间：
2013-04-05
影响因子：
3.6
通讯作者：
Sigman, Matthew S.
中科院分区：
文献类型：
--
作者：
Harper, Kaid C.;Sigman, Matthew S.
物理有机化学家的一个经典策略是使用线性自由能关系来探索反应机理。识别不对称催化反应中的这种关系有助于深入了解控制对映体选择性的关键因素，这反过来又增加了这些反应的可预测性和适用性。这次JOCSynopsis的重点是突出几个最近的例子，在这些例子中，各种参数被确定并应用于LFERs的阐明。
A classic strategy of physical organic chemists is to probe reaction mechanisms using linear free energy relationships. Identifying such relationships in asymmetric catalytic reactions provides substantial insight into the key factors controlling enantioselectivity, which in turn increases the predictability and applicability of these reactions. The focus of this JOCSynopsis is to highlight several recent examples in which various parameters were identified and applied to the elucidation of LFERs.