Smoking in pregnancy, maternal blood pressure, pregnancy outcome, baby weight and growth, and other related factors. A prospective study.

Smoking in pregnancy, maternal blood pressure, pregnancy outcome, baby weight and growth, and other related factors. A prospective study.
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怀孕期间吸烟与孕妇血压、妊娠结局、婴儿体重和生长发育等相关因素有关。

DOI:
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发表时间:
1968
期刊:
British Journal of Preventive and Social Medicine
影响因子:
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通讯作者:
C. Law
C. Law
中科院分区:
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文献类型:
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作者:
C. Russell;R. Taylor;C. Law

文献摘要

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在谢菲尔德的2个初级妇产科的200名妇女中进行了一项前瞻性调查,试图确定吸烟者所生婴儿体型较小的主要原因。胎儿的大小和生长与母亲的吸烟模式和各种相关事项有关。这些母亲根据她们的吸烟习惯被分为5组--不吸烟者、偶尔吸烟者、每天吸烟10支左右的经常吸烟者和每天吸烟20支或更多的吸烟者。当母亲的血压和吸烟进行比较时,可以看到非常显着的差异。最低血压组的吸烟者相对较多,而最高血压组的吸烟者相对较少。当妊娠结局与血压水平和母亲吸烟相关时,发现一个显着差异,表明吸烟是一种额外的危害。母亲吸烟的频率与一些因素进行了比较配偶的社会阶层母亲的年龄产次母亲的身高妇女的社会阶层父亲的教育水平配偶的年龄母亲对怀孕的态度怀孕期间的工作和后代的性别这些因素本身可能是造成胎儿体重较轻的原因.这些因素中有许多与母亲吸烟有关,但当将吸烟与其他因素的平均胎儿体重进行比较时,很明显,吸烟的影响显然与其他因素无关,无论该因素是否与吸烟有关,也无论它本身是否与较小的婴儿有关。研究结果并不支持吸烟者所生的婴儿因相关因素而较小的观点。吸烟本身是毫无疑问的。
A prospective survey was conducted among 200 women attending the 2 primary maternity units in Sheffield in an attempt to establish what factors are primarily responsible for the smaller size of the infants born to smokers. Fetal size and growth was related to the maternal smoking pattern and to various associated matters. The mothers were classified according to their smoking habits into 5 groups - nonsmokers occasional smokers regular smokers of about 10 cigarettes daily and smokers of 20 or more cigarettes daily. When maternal blood pressure and smoking were compared highly significant differences were seen. The lowest blood pressure group contained relatively more smokers and the highest blood pressure group relatively fewer. When pregnancy outcome was related to blood pressure levels and maternal smoking a significant difference was found implicating smoking as an additional hazard. The frequency of maternal smoking was compared with a number of factors - social class of consort maternal age parity maternal height social class of womans father educational level age of consort maternal attitude to the pregnancy work in pregnancy and sex of offspring - factors which might themselves be responsible for smaller fetal weight. A number of these factors were linked with maternal smoking but when mean fetal weights were compared for smoking and each of the other factors in turn it was clear that the smoking effect was clearly independent of each of the other factors regardless of whether the factor was linked with smoking and whether it was itself linked to smaller infants. The results fail to support the idea that smaller infants born to smokers are smaller because of associated factors. Smoking per se is implicated without any reasonable doubt.