Neurocognitive deficit in schizophrenia: A quantitative review of the evidence
Neurocognitive deficit in schizophrenia: A quantitative review of the evidence
复制标题
DOI：
10.1037/0894-4105.12.3.426
复制
发表时间：
1998-07-01
期刊：
影响因子：
2.4
通讯作者：
Zakzanis, KK
中科院分区：
文献类型：
--
作者：
Heinrichs, RW;Zakzanis, KK
本文对有关精神分裂症测验成绩的神经认知文献进行了定量综述。作者报告了来自204项研究的22个平均效应量，以索引精神分裂症与对照组在整体和选择性语言记忆、非语言记忆、双侧和单侧运动表现、视觉和听觉注意力、一般智力、空间能力、执行功能、语言和大脑半球间竞争转移测试表现方面的差异。对于所有22个神经认知测试变量，获得了中等到大的原始效应量（d >.60），并且没有相关的置信区间包括零。结果表明，精神分裂症的特点是广泛的认知障碍，不同程度的缺陷，在所有的能力领域测量的标准临床测试。
The neurocognitive Literature on test performance in schizophrenia is reviewed quantitatively. The authors report 22 mean effect sizes from 204 studies to index schizophrenia versus control differences in global and selective verbal memory, nonverbal memory, bilateral and unilateral motor performance, visual and auditory attention, general intelligence, spatial ability, executive function, language, and interhemispheric tactile-transfer test performance. Moderate to large raw effect sizes (d >.60) were obtained for all 22 neurocognitive test variables, and none of the associated confidence intervals included zero. The results indicate that schizophrenia is characterized by a broadly based cognitive impairment, with varying degrees of deficit in all ability domains measured by standard clinical tests.