A frequency translation approach for multichannel (13)C spectroscopy.
A frequency translation approach for multichannel (13)C spectroscopy.
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多通道 (13)C 光谱的频率转换方法。
DOI：
10.1109/embc.2015.7318671
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发表时间：
2015
期刊：
影响因子：
--
通讯作者：
Wright,StevenM
中科院分区：
文献类型：
--
作者：
Ogier,StephenE;Wright,StevenM
多通道接收器在MRI中是常见的，但是这些接收器中很少有能够在足够宽的带宽上操作以容纳1H以外的核。虽然这对于成像来说是好的，但是最近对体内NMR的兴趣激增已经产生了对接收阵列的需求，以改善其他核的通常较差的灵敏度。然而，由于多通道、多核接收器的稀缺，这些阵列的发展已经放缓。频率转换是解决这个问题的一种方法，它使用射频混频器将从多核阵列接收到的信号转换为质子频率，使窄带接收器适应多核使用。这种方法适用于各种各样的原子核，并且很容易适应质子去耦，这是使用13 C的必要条件。
Multi-channel receivers are commonplace in MRI, but very few of these receivers are capable of operating over a broad enough bandwidth to accommodate nuclei other than1H. While this is fine for imaging, the recent surge in interest in in vivo NMR has created a need for receive arrays to improve the often-poor sensitivity of other nuclei. However, the development of these arrays has been slowed by the scarcity of multi-channel, multinuclear receivers. Frequency translation is a method to solve this by using radiofrequency mixers to convert signals received from multinuclear arrays to the proton frequency, adapting narrow-band receivers to multinuclear use. This method works with a wide variety of nuclei and easily accommodates proton decoupling, a necessity for working with13C.