Some comments on the relationship of the distribution of multiple sclerosis to latitude, solar radiation, and other variables In: Studies in multiple sclerosis
Some comments on the relationship of the distribution of multiple sclerosis to latitude, solar radiation, and other variables In: Studies in multiple sclerosis
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DOI：
10.1111/j.1600-0447.1960.tb08674.x
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发表时间：
1960-01-01
期刊：
影响因子：
--
通讯作者：
WRIGHT, F. M.
中科院分区：
文献类型：
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作者：
ACHESON, E. D.;BACHRACH, C. A.;WRIGHT, F. M.
有大量证据表明，总的来说，多发性硬化症在北半球高纬度地区比在低纬度地区更常见(1、2、3、4、5)。尽管目前证据不足，但类似的关系可能存在于南半球(4)。这种关系的意义使许多人心烦意乱；种族、气候、微量元素的分布、饮食和诊断设施的可用性都被考虑在内。这篇论文证明了多发性硬化症在美国退伍军人中按出生地和纬度分布的高度相关性。试图确定与纬度相关的更有意义的变量，这些变量可能对疾病的病因有影响。
There is abundant evidence that in general multiple sclerosis is more prevalent in high latitudes in the Northern Hemisphere than in low latitudes (1, 2, 3, 4, 5). Although the evidence is at present meager, a similar relationship may hold in the Southern Hemisphere (4). The meaning of this relationship has exercised many minds (5); race, climate, the distribution of trace elements, diet, and the availability of facilities for diagnosis have all been considered. The present paper demonstrates a high degree of correlation between the distribution of multiple sclerosis in U. S. veterans by birthplace, and latitude. An attempt is made to identify more meaningful variables correlated with latitude which may have a bearing on the etiology of the disease.