Comparison of target registration errors for multiple image-guided techniques in accelerated partial breast irradiation
Comparison of target registration errors for multiple image-guided techniques in accelerated partial breast irradiation
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DOI：
10.1016/j.ijrobp.2007.11.020
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发表时间：
2008-03-15
影响因子：
7
通讯作者：
Chen, George T. Y.
中科院分区：
文献类型：
--
作者：
Gierga, David P.;Riboldi, Marco;Chen, George T. Y.
目的：外部射束加速部分乳腺照射需要对每个治疗部分的靶体积进行准确定位。使用的目标配准误差（TRE）的概念，几种方法的目标localization.Methods和材料的性能进行了比较：12例接受外部束加速部分乳腺照射的患者被纳入本研究。TRE被量化为四种图像引导方法：标准激光设置、胸壁千伏成像、手术植入夹子千伏成像和乳房三维表面成像。使用的参考表面创建一个自由呼吸的计算机断层扫描和参考表面直接捕获的三维视频成像进行了比较。呼吸运动的影响也被认为是12 patients.Results：TRE的中位数为7.1 mm（n = 94），5.4 mm（n = 81）和2.4 mm（n = 93），分别为激光，胸壁，夹对齐的8门控。基于第一部分参考表面的门控表面成像的中位TRE为3.2 mm（n = 49），使用基于计算机断层扫描的参考表面的门控表面成像的TRE为4.9 mm（n = 56）。使用第一部分参考表面进行非门控表面成像的TRE为6.2 mm（n = 25）。结论：使用三维视频直接捕获的参考表面进行表面成像的TRE和基于剪辑的设置的TRE均在1 mm以内。门控捕获对于表面成像很重要，可以减少加速部分乳腺照射中呼吸运动的影响。(C)2008年爱思唯尔公司
Purpose: External beam accelerated partial breast irradiation requires accurate localization of the target volume for each treatment fraction. Using the concept of target registration error (TRE), the performance of several methods of target localization was compared.Methods and Materials: Twelve patients who underwent external beam accelerated partial breast irradiation were included in this study. TRE was quantified for four methods of image guidance: standard laser-based setup, kilo-voltage imaging of the chest wall, kilo-voltage imaging of surgically implanted clips, and three-dimensional surface imaging of the breast. The use of a reference surface created from a free-breathing computed tomography scan and a reference surface directly captured with three-dimensional video imaging were compared. The effects of respiratory motion were also considered, and gating was used for 8 of 12 patients.Results: The median value of the TRE for the laser, chest wall, and clip alignment was 7.1 mm (n = 94), 5.4 mm (n = 81), and 2.4 mm (n = 93), respectively. The median TRE for gated surface imaging based on the first fraction reference surface was 3.2 mm (n = 49), and the TRE for gated surface imaging using the computed tomography-based reference surface was 4.9 mm (n = 56). The TRE for nongated surface imaging using the first fraction reference surface was 6.2 mm (n = 25).Conclusions: The TRE of surface imaging using a reference surface directly captured with three-dimensional video and the TRE for clip-based setup were within 1 mm. Gated capture is important for surface imaging to reduce the effects of respiratory motion in accelerated partial breast irradiation. (C) 2008 Elsevier Inc.