MICROBIAL INVESTIGATIONS IN KERATITIS AT THE SYDNEY-EYE-HOSPITAL
MICROBIAL INVESTIGATIONS IN KERATITIS AT THE SYDNEY-EYE-HOSPITAL
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DOI：
10.1111/j.1442-9071.1989.tb00564.x
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发表时间：
1989-11-01
期刊：
影响因子：
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通讯作者：
BILLSON, FA
中科院分区：
文献类型：
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作者：
MCCLELLAN, KA;BERNARD, PJ;BILLSON, FA
我们调查了1986年10月至1988年8月在悉尼眼科医院就诊的107例疑似细菌性角膜炎患者，以确定感染的频率、常见的致病微生物和那些易导致角膜感染的因素。我们发现95%的培养证实病例是由细菌引起的，其中表皮葡萄球菌和棒状杆菌占42.5%。除表皮葡萄球菌和龟分枝杆菌外，其余细菌均对庆大霉素敏感。62.6%的病例细菌和真菌培养呈阴性。回顾性分析本组患者的临床资料，单纯疱疹病毒、隐形眼镜佩戴、葡萄球菌性角膜炎、复发性糜烂是本组患者发生角膜炎的重要原因。
We investigated 107 cases of presumed microbial keratitis amongst patients presenting to the Sydney Eye Hospital between October 1986 and August 1988 to determine the frequency of infection, the common causative organisms and those factors that predispose to corneal infection. We found that 95% of culture-proven cases were caused by bacteria and that Staphylococcus epidermidis and Corynebacterium sp. accounted for 42.5% of these cases. All bacteria (except Staphylococcus epidermidis and Mycobacterium chelonae) were sensitive to gentamicin. In 62.6% of cases, cultures for bacteria and fungi were negative. Retrospective review of the clinical records of these patients showed that herpes simplex virus, contact lens wear, staphylococcal marginal keratitis and recurrent erosion were important causes of keratitis in this group.