Epithelial folding determines the final shape of beetle horns
Epithelial folding determines the final shape of beetle horns
复制标题
上皮折叠决定甲虫角的最终形状
DOI：
10.1016/j.gde.2021.03.003
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发表时间：
2021
影响因子：
4
通讯作者：
Lavine Laura C
中科院分区：
文献类型：
--
作者：
Gotoh Hiroki;Adachi Haruhiko;Matsuda Keisuke;Lavine Laura C
精心制作的装饰品和性选择的武器，例如在金龟子身上观察到的大量角，是进化的一些最引人注目的结果。这些新特性是如何产生、发展和对条件做出反应的，是由一系列复杂的相互作用决定的，这些相互作用需要环境、整个动物信号、细胞-细胞信号和细胞内信号之间的协调。内分泌因素、发育模式基因和性别特异性基因表达已被证明调节甲虫角的大小、形状和位置，但角形状的主要机制尚未被描述。最近的显微镜和计算分析结合功能遗传学方法的进展表明，模式基因与复杂的上皮折叠和运动共同作用于甲虫头角的最终形状。
The elaborate ornaments and weapons of sexual selection, such as the vast array of horns observed in scarab beetles, are some of the most striking outcomes of evolution. How these novel traits have arisen, develop, and respond to condition is governed by a complex suite of interactions that require coordination between the environment, whole-animal signals, cell–cell signals, and within-cell signals. Endocrine factors, developmental patterning genes, and sex-specific gene expression have been shown to regulate beetle horn size, shape, and location, yet no overarching mechanism of horn shape has been described.Recent advances in microscopy and computational analyses combined with a functional genetic approach have revealed that patterning genes combined with intricate epithelial folding and movement are responsible for the final shape of a beetle head horn.