FUNGAL SINUSITIS - DIAGNOSIS WITH CT AND MR IMAGING
FUNGAL SINUSITIS - DIAGNOSIS WITH CT AND MR IMAGING
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DOI：
10.1148/radiology.169.2.3174990
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发表时间：
1988-11-01
期刊：
影响因子：
19.7
通讯作者：
ROSENBAUM, AE
中科院分区：
文献类型：
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作者：
ZINREICH, SJ;KENNEDY, DW;ROSENBAUM, AE
在 293 名因慢性鼻窦炎接受计算机断层扫描 (CT)、手术和病理检查的患者中，25 名患者在病理检查时诊断为真菌性鼻窦炎。其中，22 例具有 CT 衰减增加的病灶（在 4 例患者中，平均代表性 CT 数 [Hounsfied 单位] 为 122.2 HU [SD，8.2 HU]），而 3 例则没有。 22 例患者中，19 例（76%）符合本研究的 CT 标准（假阳性率为 12%，假阴性诊断率为 12%）。 19 名患者中的 6 名和另外一名患者接受了磁共振 (MR) 成像，所有患者在 T2 加权图像上均表现出明显的低信号特征。因此，MR 成像的发现比 CT 的发现更具真菌性鼻窦炎的特征。炉原子吸收光谱分析显示，与细菌感染粘液中的铁和锰浓度相比，足菌肿中铁和锰的浓度有所增加。这一发现和真菌结核中钙的存在可以解释 MR 图像上的低信号 T2 加权信号。
Of 293 patients who underwent computed tomography (CT), surgery, and pathologic examination for chronic sinusitis, 25 had a diagnosis of fungal sinusitis at pathologic examination. Of these, 22 had foci of increased attenuation at CT (in four patients the mean representative CT number [Hounsfied unit] was 122.2 HU [SD, 8.2 HU]), and three did not. Of the 22, 19 patients (76%) met the CT criterion of this study (there was a 12% false-positive and a 12% false-negative diagnostic rate). Six of the 19 patients and one additional patient underwent magnetic resonance (MR) imaging, and all demonstrated remarkably hypointense signal characteristics on T2-weighted images. The findings at MR imaging therefore appear more characteristic of fungal sinusitis than the findings at CT. Furnace atomic absorption spectrometry showed increased concentrations of iron and manganese in mycetoma compared with their concentrations in bacterially infected mucus. This finding and the prescence of calcium in the fungal concretion may explain the hypointense T2-weighted signal on MR images.