Time course of tonal frequency-response-area of primary auditory cortex neurons in alert cats
Time course of tonal frequency-response-area of primary auditory cortex neurons in alert cats
复制标题
DOI：
10.1016/s0168-0102(03)00034-8
复制
发表时间：
2003-06-01
影响因子：
2.9
通讯作者：
Sato, Y
中科院分区：
文献类型：
--
作者：
Qin, L;Kitama, T;Sato, Y
在纯音刺激下，警觉动物A1听觉皮质的细胞表现出不同的反应时间进程：强音、相-强和相。以前，以特征频率(Cf)或在包括特征频率(Cf)在内的一系列频率中检查尖峰放电频率的时间进程。本文研究了警觉猫A1细胞在纯音刺激时频率反应面积(FRA)的时程变化。用短上升/下降时间(0.1ms~2ms)和长刺激时程(0.5S)研究其时程。FRA在时相细胞中随时间变化较大，在时相细胞中变化较小，而在时相细胞中变化不明显。FRA内的最佳反应频率(BF)在整个刺激持续时间内在强直细胞和时相细胞中是恒定的，但在时相细胞中很难定义。即使在不同带宽和光谱位置的带状噪声刺激下，相细胞的相性放电特性也保持不变。FRA时程在细胞类型之间的变异性可能在分析随时间常数变化的听觉光谱线索中发挥作用。(C)2003年爱思唯尔爱尔兰科学有限公司和日本神经科学学会。版权所有。
Cells in the A1 auditory cortex of alert animals show various response time-courses during pure-tone stimuli: tonic, phasic-tonic, and phasic. Previously the time course of the spike firing rates was examined at a characteristic frequency (CF) or in a range of frequencies including CF. We investigated time-course of the frequency-response-area (FRA) during pure-tone stimuli in A1 cells of alert cats. The short rise/fall time (0.1-2 ms) and long stimulus duration (0.5 s) was used for investigation of the time course. FRA changed with time drastically in the,phasic cells, mildly in the phasic-tonic cells, but not in the tonic cells. The best-response frequency (BF) within FRA was constant throughout the stimulus duration in the tonic and phasic-tonic cells, but was difficult to define in the phasic cells. The phasic firing properties of the phasic cells were preserved even during the bandnoise stimuli at various bandwidth and spectral locations. The variability of FRA time-course between cell types may play a role for analyzing auditory spectral cues that vary with a wide range of time constant. (C) 2003 Elsevier Science Ireland Ltd and the Japan Neuroscience Society. All rights reserved.